A dendrified bactericidal microsphere and its preparation method and application

A microsphere and tree-shaped technology, applied in the field of novel tree-shaped bactericidal microspheres and their preparation, can solve the problems of poor peeling and washing effects, high transportation and storage costs, toxic by-products, etc., so as to avoid secondary pollution, overcome the Residual water body, the effect of improving the bactericidal power

Active Publication Date: 2020-08-25
ZHEJIANG GONGSHANG UNIVERSITY
View PDF2 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Sterilization refers to the killing of pathogenic bacteria in the object. There may be non-pathogenic bacteria such as spores or thermophilic bacteria in the object. The above two types of substances can achieve the effect of sterilization, but traditional fungicides also have insurmountable shortcomings : When the content of organic matter in the water source is slightly high, oxidizing fungicides such as chlorine gas sterilization will produce chlorinated organic matter, which can cause cancer; and the stability is not good, easy to decompose, the cost of transportation and storage is high, and there are potential threats such as explosion; in industrial water treatment , Poor peeling and washing effect on bacterial scale and slime
Since the use of water-soluble fungicides in water and liquid food will cause certain hazards, oxidizing fungicides will produce toxic by-products, and non-oxidizing fungicides are residual toxicity problems, and there is a risk of "secondary pollution"

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A dendrified bactericidal microsphere and its preparation method and application
  • A dendrified bactericidal microsphere and its preparation method and application
  • A dendrified bactericidal microsphere and its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] In this embodiment, the dendritic bactericidal microspheres are prepared according to the following method:

[0046] (1) Synthesis of G0.5: Weigh 15 mg of chlorine balls and place them in a 100 mL three-neck flask, add 25 mL of reaction solvent DMF, soak for 12 hours to fully swell the carrier. Add ethylenediamine and 2.25g catalyst metal sodium in the three-necked bottle then, the mol ratio of chlorine ball and ethylenediamine is 1:3, feeds N 2 protection, stirring the reaction at 90°C for 10h, and filtering off the reacted G0.5. Rinse three times with the reaction solvent DMF, and soak in 1mol / L NaOH for 8 hours. Then rinse with absolute ethanol, acetone, and ether repeatedly for 3 times, and put it into a 50°C vacuum drying oven to dry for later use;

[0047] (2) Synthesis of G1.0: Weigh 15 mg of G0.5 with the largest grafting amount and place it in a 100 mL three-neck flask, add 25 mL of reaction solvent methanol to soak for 12 hours, add methyl acrylate dropwise ...

Embodiment 2

[0054] In this embodiment, the dendritic bactericidal microspheres are prepared according to the following method:

[0055] (1) Synthesis of G0.5: Weigh 15 mg of chlorine balls and place them in a 100 mL three-neck flask, add 25 mL of reaction solvent DMF, soak for 12 hours to fully swell the carrier. Add ethylenediamine and 2.25g catalyst metal sodium in the three-necked bottle then, the mol ratio of chlorine ball and ethylenediamine is 1:4, feeds N 2 Protected, stirred and reacted at 100°C for 11h, and the reacted G0.5 was filtered off. Rinse three times with the reaction solvent DMF, and soak in 1mol / L NaOH for 8 hours. Then rinse with absolute ethanol, acetone, and ether repeatedly for 3 times, and put it into a 50°C vacuum drying oven to dry for later use;

[0056] (2) Synthesis of G1.0: Weigh 15 mg of G0.5 with the largest grafting amount and place it in a 100 mL three-neck flask, add 25 mL of reaction solvent methanol to soak for 12 hours, add methyl acrylate dropwise...

Embodiment 3

[0063] In this embodiment, the dendritic bactericidal microspheres are prepared according to the following method:

[0064] (1) Synthesis of G0.5: Weigh 15 mg of chlorine balls and place them in a 100 mL three-neck flask, add 25 mL of reaction solvent DMF, soak for 12 hours to fully swell the carrier. Add ethylenediamine and 2.25g catalyst metal sodium in the three-necked bottle then, the mol ratio of chlorine ball and ethylenediamine is 1:5, feeds N 2protection, stirring the reaction at 110°C for 12h, and filtering off the reacted G0.5. Rinse three times with the reaction solvent DMF, and soak in 1mol / L NaOH for 8 hours. Then rinse with absolute ethanol, acetone, and ether repeatedly for 3 times, and put it into a 50°C vacuum drying oven to dry for later use;

[0065] (2) Synthesis of G1.0: Weigh 15 mg of G0.5 with the largest grafting amount and place it in a 100 mL three-neck flask, add 25 mL of reaction solvent methanol to soak for 12 hours, add methyl acrylate dropwise ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention provides a novel tree-like sterilization micro-sphere, a preparation method thereof and an application. The preparation method includes the steps: taking chloromethylation polystyrene micro-spheres as an initiating core; taking ethidene diamine and methyl acrylate as a molecular chain; performing synthesis and fixing on 3-generation PAMAM (polyamidoamine) tree-like macromolecules by the aid of Michael addition reaction and a divergent method; taking sulfanilamide as a functional group, and performing quaternized modification to obtain the tree-like sterilization micro-sphere. The novel tree-like sterilization micro-sphere avoids 'secondary pollution' of water caused by traditional sterilizing agents and can effectively solve the problem that soluble sterilizing agents remain in the water, so that food safety is ensured, the application range of the sterilizing agents is widened, the sterilization micro-sphere can be recovered and reused, and the use ratio of the resources can be effectively increased.

Description

technical field [0001] The invention belongs to the technical field of synthesis and modification of dendrimers, and in particular relates to a novel dendritic bactericidal microsphere and its preparation method and application. Background technique [0002] Water is the source of life, the basis for human survival and development, and one of the important natural resources necessary for the development of the world economy. At present, the average amount of water available per capita in the world is 7,300 cubic meters per year, which has dropped by 37% compared with 1970. In the late 1980s, the actual freshwater utilization of the earth was about 300 billion m 3 per year, accounting for 1-3% of the total available water sources, but with the rapid development of industry and population in modern society, people's demand for water has increased by hundreds of millions, and the requirements for water quality have also become higher and higher. The amount of water available ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Patents(China)
IPC IPC(8): C08G83/00A01N41/08A01P1/00C02F1/50
CPCA01N41/08C02F1/50C08G83/004
Inventor 熊春华阎亚利逯丽
Owner ZHEJIANG GONGSHANG UNIVERSITY
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap