Direct oral decumbent corydalis tuber powder Chinese herbal piece

Abstract

The invention provides a direct oral decumbent corydalis tuber powder Chinese herbal piece. A preparation process of the direct oral decumbent corydalis tuber powder Chinese herbal piece is as follows: (1) after being inspected, cleaned and dried, a raw material decumbent corydalis tuber is ground, so that an intermediate is obtained; (2), the intermediate is inspected, and after the intermediate is packaged, electron beam irradiation is carried out for sterilization; (3) final product standard inspection is carried out, and after packaging, the final product is obtained. In step (1), the grinding conditions are as follows: in a grade D clean area, a dust suction type cryogenic system grinding technology is applied to grind the raw material decumbent corydalis tuber into 100 to 300 meshes; and in step (2), the exposure dose of electron beam irradiation for sterilization is 3kGy to 10kGy. The total amount of an aqueous extract of the decumbent corydalis tuber (powder) product and the total amount of water-dissolved protopine and palmatine chloride in the aqueous extract can be increased by 30 to 45 percent in comparison with the total amount of an aqueous extract of the fine powder standard (100 meshes) of Chinese Pharmacopoeia and the total amount of water-dissolved protopine and palmatine chloride in an aqueous extract, and a microbial limit test result can fully come up to a related direct oral piece standard.

Description

Technical field [0001] The invention relates to a summer powder-free direct oral Chinese medicine decoction piece, which belongs to the technical field of medicine. Background technique [0002] Summer inaction, Papaveraceae Corydalis perennial herb Corydalis decumbens Corydalis decumbens [0003] (Thunb.) The dry tuber of Pers., also known as Fudiyanhusuo, Fudiyuanhu, Viola sessile, Xia Wuzong. Xiawuwu completes the life process of flowering and fruiting before the arrival of early summer, and then begins the withering of the whole plant. When the summer heat comes, there will be no plants for Xiawuwu on the ground, hence the name "Xiamenwu" [0004] Xiatianwu is a common Chinese medicinal material. It is warm in nature and pungent in taste. It has the effect of activating blood and relieving pain. It has healing effect on the treatment of congestion, redness, joint pain, bruises and rheumatoid. Moreover, the alkaloids contained in Tianwuwu have a therapeutic effect on cardiovascu...

AI Technical Summary

Problems solved by technology

Physical sterilization methods such as dry heat, high temperature and high pressure steam, chemical sterilization methods such as ethylene oxide, and gamma ray sterilization methods such as cobalt-60 all have major defects, and some of the sterilization methods have poor sterilization effects. Some destroy and partially change the chemical properties of active ingredients of different structural types contained in traditional Chinese medicines of different textures, some leave nuclear substance residues, and some have pollution factors, etc.

[0009] Direct oral Chinese herbal decoction pieces are a new type of modern Chinese herbal decoction pieces that have just been defined by the state in recent years. In addition to the microbial limit standards for direct oral decoction pieces listed in the fourth part of the "Chinese Pharmacopoeia" 2015 edition, there is still no national unified quality enforcement of direct oral Chinese herbal medicine decoction pieces. Standard, summer-free (powder) products are no exception

In addition, because the chemical components of different types of structures contained in each herb are very complex, and the quality is different in different places of origin, the content quality requirements are often based on the content of its index components or active components reaching a certain value (except for toxic components). ), and most of the active ingredients are stored in its cells. For various reasons, there is no statistical and scientific "expiration date" for summer powder as a drug.

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