Electronic capsule for digestive tract and drug delivery method

An electronic capsule and digestive tract technology, applied in the field of medical supplies, can solve problems such as complex drive device structure, uncontrollable drug release dose, and insufficient reliability, so as to improve rapid real-time performance, reduce the number of unknown quantities, and avoid rapid attenuation Effect

Active Publication Date: 2020-06-16
UNIV OF SHANGHAI FOR SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The current fixed-point drug release system for the digestive tract has the following disadvantages: the structure of the driving device is complex and the reliability is insufficient; the release rate of the drug is low, the release dose is uncontrollable, and cannot adapt to the drug release requirements of each segment of the digestive tract; the trigger time is long Long, may cause the applicator to miss the target area; can only complete a single application action

Method used

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  • Electronic capsule for digestive tract and drug delivery method
  • Electronic capsule for digestive tract and drug delivery method
  • Electronic capsule for digestive tract and drug delivery method

Examples

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Embodiment Construction

[0022] see figure 1 , the electronic capsule used in the digestive tract of the present invention comprises a shell 1 and a one-way valve for drug delivery 2, a first permanent magnet 3, a drug storage bag 4, a thin cylindrical sheet 5, an electromagnetic coil 6, a second Permanent magnet 7 , position tracking and drive control module 8 . The first permanent magnet 3 is provided with an axial through hole, and the front and rear of the through hole are respectively communicated with the one-way valve and the medicine storage bag. Both the first permanent magnet 3 and the second permanent magnet 7 are cylindrical permanent magnets magnetized in the axial direction, and are arranged with opposite magnetic poles to form a gradient magnetic field. The electromagnetic coil 6 is a movable electromagnetic coil, and the excitation signal of the electromagnetic coil is provided by the position tracking and driving control module 8 . When a current in a set direction is passed through...

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Abstract

The invention discloses an electronic capsule applied to a digestive tract. The electronic capsule comprises a shell as well as a drug application one-way valve, a first permanent magnet, a drug storage bag, a thin cylindrical sheet, an electromagnetic coil, a second permanent magnet and a position tracking and driving control module. A drug delivery method based on the electronic capsule, on the basis of a three-axle geomagnetic field detection principle and a principle of quaternion rotation as well as an alternating magnetic vector sensing principle, and in the combination with attitude angle detection, comprises the following steps: receiving a magnetic vector signal and an azimuth angle signal, which are transmitted from the electronic capsule, by virtue of an in-vitro radio-frequency receiver / transmitter in a wireless mode, and solving the signals by virtue of a data processing platform in real time, so that position tracking of the electronic capsule is achieved; and triggering the drug application one-way valve to implement drug release by virtue of a radio-frequency signal when the electronic capsule reaches a target area. According to the electronic capsule provided by the invention, drug application reliability and rapidity as well as controllability over a drug release dose and a drug release speed are achieved; and a drug release action can be implemented for several times.

Description

technical field [0001] The invention relates to medical supplies, in particular to an electronic capsule and a drug delivery method for the digestive tract. Background technique [0002] As my country's aging population grows by more than 10 million each year, the problem of population aging has become increasingly prominent. The diseases of the elderly are mostly chronic diseases, among which gastrointestinal diseases are one of the more prominent ones. In addition, the acceleration of modern life rhythm and the increase of life pressure have increased the incidence of chronic digestive tract diseases year by year. [0003] Most of the current chronic diseases of the gastrointestinal tract require medication for long-term treatment. Because oral medication is difficult to reach the lesion directly or the dose to reach the lesion is too small, oral medication is poor or ineffective. Therefore, if targeted drug delivery therapy can be carried out directly and efficiently in...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61M31/00
CPCA61M31/002A61M2202/06A61M2210/1042A61M2202/0007A61M31/00
Inventor 郭旭东王殊轶崔海坡葛斌严荣国鲁正平许堂成
Owner UNIV OF SHANGHAI FOR SCI & TECH
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