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Drug delivery capsule and drug delivery method

A technology for medicines and capsules, applied in the field of medical supplies, can solve problems such as long triggering time and missing target areas of the drug application device, and achieve the effects of improving solution accuracy, improving fast real-time performance, and reducing the number of unknowns

Active Publication Date: 2020-09-08
UNIV OF SHANGHAI FOR SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The current fixed-point drug release system for the digestive tract has the following disadvantages: the trigger time is long, which may cause the drug application device to miss the target area; it can only complete a single drug application action

Method used

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  • Drug delivery capsule and drug delivery method
  • Drug delivery capsule and drug delivery method

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Embodiment Construction

[0020] see figure 1 , with reference to figure 2 , the drug delivery capsule of the present invention, comprising a housing 1 and a drug application check valve 2, a first permanent magnet 3, a drug storage bag 4, an electromagnetic coil 5, a second permanent magnet 6, an azimuth measurement and an excitation The control module 7 is provided with a photoelectric pair tube 8 on the periphery of the electromagnetic coil 5, wherein the first permanent magnet is provided with an axial through hole, and the front and back of the through hole communicate with the one-way valve and the medicine storage bag respectively.

[0021] The first permanent magnet and the second permanent magnet are cylindrical permanent magnets magnetized along the axial direction, and are arranged in opposite poles to form a gradient magnetic field. The electromagnetic coil is a movable electromagnetic coil. The excitation signal of the electromagnetic coil is provided by the azimuth measurement and exci...

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Abstract

The invention discloses a drug delivery capsule, which comprises a shell as well as a drug application one-way valve, a first permanent magnet, a drug storage bag, an electromagnetic coil, a second permanent magnet and an azimuth measuring and excited magnetic control module which are sequentially arranged in the shell, wherein opposite photoelectric cells are arranged on the periphery of the electromagnetic coil. The drug delivery method based on the drug delivery capsule, on the basis of a double-magnetic vector detection principle, comprises the following steps: receiving a magnetic vector signal and an azimuth angle signal of the drug delivery capsule by virtue of an in-vitro radio-frequency receiver / transmitter in a wireless mode, and solving the signals by virtue of a data processing platform in real time, so that position tracking of the drug delivery capsule is achieved; and triggering the drug application one-way valve to implement drug release by virtue of a radio-frequency signal when the data processing platform calculates that the capsule has entered into a drug application target area. According to the drug delivery capsule and the drug delivery method provided by the invention, by arranging a gradient magnetic field, the circumstance that driving force of the magnetic field becomes attenuated quickly as moving travel of the electromagnetic coil is increased and the distance between the electromagnetic coil and a magnetic field source is increased when a drug application dose is relatively high is prevented, and high-dose drug release is achieved.

Description

technical field [0001] The invention relates to medical supplies, in particular to a medicine delivery capsule and a medicine delivery method. Background technique [0002] Most of the current gastrointestinal chronic diseases require medication for long-term treatment, but the effect of drug treatment is not good; in addition, for the hyperplastic lesions in the digestive tract, it is difficult to directly reach the lesion or the dose to reach the lesion is too small, resulting in Failure of oral drug therapy. Therefore, if drug therapy can be directly and efficiently administered at inflammation, wounds, and lesions, it can not only enhance the absorption of drugs to achieve efficient treatment, but also reduce the side effects of drugs, so that interventional medical operations such as targeted drug delivery can be implemented safely and non-invasively. . [0003] The Enterion TM pill developed by Phaeton Research (Nottingham, UK) has a shape of Φ1lmm×32mm, uses a high-...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61M31/00
CPCA61M31/00
Inventor 郭旭东葛斌王殊轶崔海坡鲁正平许堂成
Owner UNIV OF SHANGHAI FOR SCI & TECH
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