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A kind of Chinese herbal medicine composition for treating and/or preventing prostate disease and its preparation method and application

A Chinese herbal medicine composition, prostate technology, applied in the field of medicine, can solve the problems of delayed disease, high price, high treatment cost for patients, etc., achieve the effect of reducing side effects, low cost, and inhibiting the development of prostatic hypertrophy

Active Publication Date: 2021-01-15
SHENZHEN XIANHU BOTANICAL GARDEN ADMINISTRATION
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, most of the Western medicines for the treatment of prostate diseases are produced by foreign-funded or joint-venture pharmaceutical factories, and the price is relatively high. Many patients cannot bear the high treatment costs due to economic reasons, thus delaying their treatment; Toxic and side effects are also relatively obvious, so Chinese patent medicines have their unique advantages in the treatment of protracted prostatic diseases

Method used

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  • A kind of Chinese herbal medicine composition for treating and/or preventing prostate disease and its preparation method and application
  • A kind of Chinese herbal medicine composition for treating and/or preventing prostate disease and its preparation method and application
  • A kind of Chinese herbal medicine composition for treating and/or preventing prostate disease and its preparation method and application

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preparation example Construction

[0077]The second aspect of the embodiment of the present invention provides a preparation method of a Chinese herbal medicine composition for treating and / or preventing prostate diseases, including:

[0078]Take the crude drug in parts by weight described in the first aspect, after crushing, add 20%-90% ethanol for soaking extraction or reflux extraction, and then filter, the filtrate is concentrated by rotary evaporation and freeze-dried to prepare The Chinese herbal medicine composition.

[0079]In the embodiment of the present invention, the crude drug is crushed to 80 mesh.

[0080]In the embodiment of the present invention, the extraction method of the Chinese herbal medicine composition of the present invention may be immersion extraction or reflux extraction, and these extraction methods are simple and easy to operate, and the extraction rate is relatively high.

[0081]In the embodiment of the present invention, the specific operation of the soaking extraction includes: adding ethanol w...

Embodiment 1

[0089]A preparation method of a Chinese herbal medicine composition for treating and / or preventing prostate diseases, comprising:

[0090]Take the following raw materials by weight:

[0091]20 parts of Astragalus

[0092]15 Codonopsis

[0093]15 parts of Lingzhi

[0094]Acanthopanax 15 parts

[0095]10 copies of Ligustrum

[0096]10 servings of schisandra

[0097]10 copies of Baizhu

[0098]5 servings of licorice.

[0099]Crush the above weight parts of the API to 80 mesh, add 85% edible ethanol and soak 3 times. During each soak, the liquid-to-solid ratio of ethanol to API is 50mL / g, and soak for 24 hours each time. The temperature at that time was 25°C, the extract was combined and filtered, and the filtrate was concentrated by rotary evaporation and freeze-dried to prepare the Chinese herbal medicine composition.

Embodiment 2

[0101]A preparation method of a Chinese herbal medicine composition for treating and / or preventing prostate diseases, comprising:

[0102]Take the following raw materials by weight:

[0103]15 parts of Astragalus

[0104]10 copies of Codonopsis

[0105]10 parts of Lingzhi

[0106]Acanthopanax senticosus 10 parts

[0107]5 copies of Ligustrum

[0108]5 servings of schisandra

[0109]5 copies of Baizhu

[0110]1 part of licorice.

[0111]The above weight parts of the API are crushed to 80 meshes, and edible ethanol with a concentration of 20% is added to soak twice. During each soak, the liquid-solid ratio of ethanol to the API is 1 mL / g, and the soak is 30 hours each time. When the temperature is 80°C, the extracts are combined and filtered, and the filtrate is concentrated by rotary evaporation and freeze-dried to prepare the Chinese herbal medicine composition.

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Abstract

The invention provides a Chinese herbal medicinal composition for treating and / or preventing prostate disease. The Chinese herbal medicinal composition is prepared from the following crude drugs in parts by weight: 15 to 25 parts of radix astragali, 10 to 20 parts of radix codonopsis, 10 to 20 parts of lucid ganoderma, 10 to 20 parts of acanthopanax root, 5 to 15 parts of fructus ligustri lucidi, 5 to 15 parts of fructus schisandrae, 5 to 15 parts of rhizoma atractylodis macrocephalae and 1 to 10 parts of radix glycyrrhizae. The Chinese herbal medicinal composition has a remarkable inhibiting effect on prostate cancer and prostatic hyperplasia; in addition, the crude drugs are common Chinese herbal medicines recorded in Chinese Pharmacopoeia, and the Chinese herbal medicinal composition has the advantages of safe and reliable medication, low cost and good effect. The invention further provides a preparation method of the Chinese herbal medicinal composition. The preparation method comprises the following steps: taking the crude drugs by weight parts, crushing and then adding ethanol with the concentration of 20 to 90 percent for carrying out soaking extraction or refluxing extraction; filtering, and carrying out rotary evaporation and concentration and freeze drying on filtrate, thus obtaining the Chinese herbal medicinal composition. The preparation method is simple and easy in operation. The invention further provides application of the Chinese herbal medicinal composition to preparation of a medicine for treating and / or preventing the prostate disease.

Description

Technical field[0001]The present invention relates to the field of medicine, in particular to a Chinese herbal medicine composition for treating and / or preventing prostate diseases, and a preparation method and application thereof.Background technique[0002]Prostate disease is a common disease in adult men, including enlarged prostate and prostate cancer. Prostatic hypertrophy (BPH), also known as hyperplasia, is a special histopathological disease characterized by the proliferation of stromal and epithelial cells. BPH can cause benign prostate enlargement and benign prostate obstruction that can be shown by urodynamics. Prostate diseases such as prostatic hypertrophy are chronic diseases with a high incidence rate and a wide range of patients. Patients need long-term medication and have a large market space. At present, Western medicines for the treatment of prostate diseases are mostly produced by foreign-funded or joint-venture pharmaceutical companies, and their prices are relati...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/638A61K36/79A61P13/08A61P35/00
CPCA61K36/074A61K36/254A61K36/284A61K36/344A61K36/481A61K36/484A61K36/57A61K36/638A61K36/79A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 陈涛杜才干
Owner SHENZHEN XIANHU BOTANICAL GARDEN ADMINISTRATION