Low temperature reaction kettle provided with feeding device

Abstract

A low temperature reaction kettle provided with a feeding device comprises a low temperature reaction kettle body, the feeding device, a low temperature control device, a stirring device and a centrifugal solid-liquid separation device, the top of the low temperature reaction kettle body is provided with a feeding opening, the bottom of the low temperature reaction kettle body is provided with a discharging opening, the feeding device comprises a bent discharging tube, a homogenizing tube, a filler box and a fan, two ends of the homogenizing tube are openmouthed, one end of the homogenizing tube is positioned in the low temperature reaction kettle body, and the tube wall of one end, positioned in the low temperature reaction kettle body, of the homogenizing tube is provided with a plurality of groups of holes. The low temperature reaction kettle provided with the feeding device has a reasonable structure design, and adopts electric slide tables to drive fan type stirring blades, and a material automatically rotates due to a fluid principle in the up-and-down movement process of the stirring blades in order to reach a stirring purpose, so the motor power is reduced, the generated heat is reduced, the precipitation reaction efficiency is high, and the kettle has very high practical values.

Description

technical field [0001] The invention relates to the technical field of white oil production, in particular to a low-temperature reaction kettle with a feeding device. Background technique [0002] Tenofovir (Compound I), also known as Tenofovir, Chinese full name: (R is used in the secondary precipitation reaction kettle of Tenofovir production line)-9-(2-phosphomethoxypropyl)-adeno Purine is used in the secondary precipitation reaction of tenofovir production line, which is an AIDS antiviral drug. Tenofovir is also a better AIDS antiviral drug. Tenofofumarate fumarate is used in the tenofovir production line The key intermediate of vir dipivoxil (used in the secondary precipitation reactor II of tenofovir production line for the secondary precipitation reactor of tenofovir production line). In the tenofovir production line, it is necessary to stir the primary reaction solution with brine to precipitate HPA product crystals. The existing low-temperature reactor uses a high-...

AI Technical Summary

Problems solved by technology

In the tenofovir production line, it is necessary to stir the primary reaction solution with brine to precipitate HPA product crystals. The existing low-temperature reactor uses a high-power motor for stirring, which not only wastes energy, but also increases additional heat and hinders the precipitation. reaction

At present, when adding auxiliary materials in the reactor, it is added directly at the feeding port. When the powder is added, it will fall into a ball on the liquid surface in the reactor, and it will take a long time to mix with the liquid surface of the reactor. The liquid in the reactor is fused, which increases the stirring time. At the same time, when the material is discharged, the gas in the reactor overflows from the discharge port, polluting the working environment

Images