Method for obtaining grade standard images of brain glioma
A technology of glioma and acquisition method, which is applied in the field of acquisition of level standard maps, and can solve problems such as growth time and long time
Active Publication Date: 2017-11-21
江苏拉曼医疗设备有限公司
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However, the waiting time for the biopsy results is longer, which increases the time of the entire operation process, and the patient also has certain risks during the waiting process
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[0025] Specific embodiments of the present invention will be described in detail below in conjunction with the accompanying drawings. It should be understood that the specific embodiments described here are only used to illustrate and explain the present invention, and are not intended to limit the present invention.
[0026] Please refer to Figure 1 to Figure 5 , figure 1 It is the Raman spectrum of grade 0 glioma, figure 2 It is the Raman spectrum of grade I glioma, image 3 It is the Raman spectrum of grade II glioma, Figure 4 It is the Raman spectrum of grade III glioma, Figure 5 It is the Raman spectrum of grade IV glioma.
[0027] In a specific embodiment, the present invention provides a method for obtaining a glioma grade standard map, comprising the following steps:
[0028] Step S1, using the probe of the Raman detection system to irradiate brain tissue samples of different glioma grades to excite Raman signals, and obtain Raman spectra through a spectrum a...
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The invention discloses a method for obtaining grade standard images of brain glioma. The method comprises the following steps: utilizing a probe of a Raman detection system to irradiate brain tissue samples at different glioma grades and exciting Raman signals and obtaining Raman spectrums through a spectrum analyzer; then, comparing Roman peaks corresponding to proteins with Roman peaks corresponding to lipids to obtain ratios of all grades in Raman spectrums at all grades of brain gliomas; taking brain glioma grades and ratios of all grades as horizontal ordinates and vertical ordinates to obtain the grade standard images of brain gliomas. The standard images of brain glioma can assist doctors to carry out in-situ diagnoses in a real-time manner. During a brain operation, the probe of the Raman system is utilized for irradiating brain tissues of a patient. After Raman spectrums are obtained, data is processed such that the obtained result is compared with the standard images. Lesions of brain tissues of the patient can be obtained so that in-situ diagnoses of brain gliomas can be realized in a real-time manner. As a result, the method for obtaining grade standard images of brain glioma does not only accurately obtain grades of brain gliomas but also shortens the operation time and reduces the risk.
Description
technical field [0001] The invention relates to a method for acquiring a grade standard map of brain gliomas. Background technique [0002] Glioma is the most common primary brain tumor arising from the canceration of glial cells in the brain and spinal cord. [0003] The diagnosis of glioma plays a crucial role in the treatment of glioma. Currently, commonly used diagnostic methods include MRI and tissue biopsy. [0004] Usually, MRI is used to obtain tumor information, including tumor local information, size, and biochemical composition at the molecular level, to prepare for tumor surgery. However, due to the time difference between MRI and surgery, the tissue, contour and position of the tumor will deviate to a certain extent during the operation, and the actual situation of the tumor during the operation will have a certain deviation from the tumor information of the MRI. [0005] Tissue biopsy is a biopsy of brain tissue. The biopsy process is based on the visualizat...
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Login to View More IPC IPC(8): A61B5/00A61B90/00
CPCA61B5/0042A61B5/0075A61B90/06
Inventor 周岩刘承惠
Owner 江苏拉曼医疗设备有限公司