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Curcumin composition with effect of preventing and treating diabetes mellitus and complications

A technology of curcumin and composition, applied in the field of compositions made of natural products, can solve problems such as difficult quality control, unclear medicinal effect material basis, complex chemical composition, etc., and achieves low price, regulation of human immunity, composition Well-defined effects

Active Publication Date: 2017-11-24
长春康彼达科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the chemical composition of traditional Chinese medicine is complex, the material basis of medicinal effect is not clear, and it is difficult to control the quality

Method used

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  • Curcumin composition with effect of preventing and treating diabetes mellitus and complications
  • Curcumin composition with effect of preventing and treating diabetes mellitus and complications
  • Curcumin composition with effect of preventing and treating diabetes mellitus and complications

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] Embodiment 1, Extract preparation

[0046] (1) Grind turmeric into coarse powder, use 8 times the amount of 80% ethanol to reflux extract for 3 times, extract for 2 hours each time, filter, reclaim ethanol from the filtrate, concentrate to alcohol content of 20%, and pass through pre-treated D -101 macroporous resin column, first eluted with 20% ethanol, then eluted with 80% ethanol, collected 80% ethanol eluate, recovered ethanol, dried to obtain curcumin;

[0047] (2) Take the Grape dentata, extract 4 times with 70% ethanol under reflux, extract for 1 hour each time, filter, add 0.5% medicinal activated carbon in the volume of the liquid medicine, filter, reclaim the ethanol from the filtrate, heat and dissolve with 50 times the amount of water , concentrate, filter, wash the filter residue with water, and dry to obtain dihydromyricetin;

[0048] (3) Get mulberry branch, reflux extraction with 8 times the amount of 65% ethanol for 2 times, each time for 3 hours, com...

Embodiment 2

[0049] Example 2 , (capsules)

[0050] Weigh 50 g of curcumin, 100 g of dihydromyricetin, 200 g of Mori twig extract, and 25 g of starch, mix them uniformly, granulate, dry, granulate, pack into capsules, and make 1000 capsules to obtain final product. 2 capsules each time, 2 times a day.

Embodiment 3

[0051] Example 3 ,(tablet)

[0052] Weigh 50 g of curcumin, 100 g of dihydromyricetin, 200 g of mulberry branch extract, and 25 g of starch, mix them uniformly, granulate, dry, granulate, and compress into tablets to make 1000 tablets, to obtain the final product. 2 tablets each time, 2 times a day.

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Abstract

The invention relates to a composition using curcumin, dihydromyricetin and mulberry twig extract as main components. The composition has the effect of preventing and treating diabetes mellitus and complications. The composition comprises three substances with different pharmaceutical effects, plays a role in reducing blood sugar by utilizing acting principles and target points of the substances with different pharmaceutical effects, has the characteristics of low taking dosage and homology of medicines and foods, and is a safe and effective health-care product. Proved by experiments, the composition has stronger activity for reducing the blood sugar than single curcumin, dihydromyricetin or mulberry twig extract. The composition embodies the characteristic of synergistic effect of a compound composition and can be used for preparing medicines and health-care foods with the effects of reducing the blood sugar and preventing the diabetes mellitus and the complications.

Description

technical field [0001] The invention belongs to the fields of medicine and food, and relates to a composition made of natural products capable of preventing and treating related diseases such as diabetes and its complications. Background technique [0002] Diabetes mellitus is a chronic endocrine and metabolic disease caused by absolute or relative insulin deficiency, and its main feature is the coexistence of high blood sugar and various complications. The incidence of diabetes in my country shows an increasing trend year by year, and 90% of them are non-insulin-dependent diabetes. The total number of patients is 40 million. According to the WHO forecast, by 2025, the number of diabetic patients in my country will exceed 50 million. Diabetes mellitus is characterized by chronic hyperglycemia accompanied by disorders of sugar, fat and protein metabolism caused by defects in insulin secretion and action. Its long-term hyperglycemia and hyperlipidemia are important causes of...

Claims

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Application Information

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IPC IPC(8): A61K36/605A61P3/10A61K31/12A61K31/352
CPCA61K31/12A61K31/352A61K36/605A61K2236/333A61K2236/39A61K2236/55A61K2300/00
Inventor 胡铭南敏伦赫玉芳姜文月邹慧曲佳乐赵全成
Owner 长春康彼达科技有限公司
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