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A composition for preventing and treating renal osteodystrophy

A technology of malnutrition and composition, applied in the field of prevention and treatment of osteoporosis, to achieve the effect of improving absorption rate, preventing and treating renal malnutrition, and improving quality of life

Active Publication Date: 2019-09-03
贵州亿为康生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0011] In addition, although there are many varieties of calcium and zinc products on the market, most of them are mainly promoting their single-effect or functional multi-dimensional element products, rather than focusing solely on the treatment and health care of renal osteodystrophy and renal anemia

Method used

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  • A composition for preventing and treating renal osteodystrophy

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0068] The product formula is as follows (taking 1000 doses of the product per recipe as an example):

[0069]

Embodiment 2

[0070] Embodiment 2: the preparation method of tablet (trial 1 and 2)

[0071] Get formula quantity calcium aspartate, magnesium aspartate, zinc aspartate and manganese aspartate, add filler respectively in test 1 and 2 (microcrystalline cellulose: the weight ratio of compressible starch is 3: 1) 125g, 60g, add 4% sodium carboxymethyl starch after mixing, granulate with 1% sodium carboxymethylcellulose after mixing, then add 0.5% magnesium stearate, mix After evenly compressing the tablet, coating, that is to say. The amount of the auxiliary materials is the percentage of the total weight of the tablet. Embodiment 3: the preparation method of granule (test 3 and 4)

Embodiment 3

[0072] Take the formula amount of calcium aspartate, magnesium aspartate, zinc aspartate and manganese aspartate, add dextrin and sucrose to the full amount, and the mass ratio of sucrose: dextrin is 3:1, mix well Finally, granulate with 8%-12% starch slurry, dry, granulate, pack into bags, and obtain.

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Abstract

The invention relates to the fields of medicine and health care, in particular to a composition for preventing and curing renal osteodystrophy and a preparation thereof. The composition is prepared from the following components in parts by weight: 2440 to 6910 parts of calcium aspartate, 1040 to 2360 parts of magnesium aspartate, 37 to 63 parts of zinc aspartate and 21 to 35 parts of manganese aspartate. The composition is prepared through reasonable compatibility of medicines and a scientific method, so that the product is stable in effect, convenient to use, quick to become effective and effective in treatment, has the effects of preventing and curing renal osteodystrophy and strengthening osteotrophy, and is free of toxic and / or side effects; through mutual effects of the effective active ingredients, the composition disclosed by the invention is high in bioavailability and reaches a synergistic interaction effect. The composition is safe, scientific, simple and effective.

Description

technical field [0001] The invention relates to the technical field of prevention and treatment of osteoporosis, in particular to a composition for preventing and treating renal osteodystrophy and its preparation. Background technique [0002] Chronic renal failure refers to a clinical syndrome composed of a series of symptoms and metabolic disorders caused by various kidney diseases leading to progressive and irreversible decline in renal function until the loss of function, referred to as chronic renal failure; the end stage of chronic renal failure is People often say uremia. Once a patient suffers from this disease, he not only bears huge economic and psychological pressure, but also suffers from various complications physically: renal osteodystrophy, renal anemia, renal malnutrition, etc. Among them, renal osteodystrophy is the most difficult to control. Renal osteodystrophy is severe osteoporosis in human body. [0003] Renal osteodystrophy is a bone disease caused ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/198A61K9/28A61K9/16A61K9/08A61P3/02A61P19/10A61P13/12
Inventor 谢志强
Owner 贵州亿为康生物科技有限公司
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