The invention provides a composition and a preparation for regulating children's spleen, stomach, intestine and growth and development. A medicinal and edible homologous composition comprises rhizomaPolygonati, fructus crataegi, fructus Hordei Germinatus, pericarpium Citri Tangerinae, endothelium corneum Gigeriae Galli, radix Glycyrrhizae, semen lablab album, rhizoma Dioscoreae, Poria, radix Platycodonis, rhizoma Zingiberis, Coicis semen, semen Nelumbinis, fructus Amomi, casein phosphopeptide, calcium aspartate, ferrous glycine, zinc gluconate, vitamin B2, vitamin B6, vitamin D3 and vitamin C. The present invention is effective in treating various diseases caused by weakness of spleen and stomach in children, Intestinal disorder, growth retardation, etc. have good recuperation effect, avoid the harm caused by western medicine single trace element supplement, retain the advantages of traditional Chinese medicine homologous food balance homogeneous recuperation, in order to ensure the efficacy of drugs, but also avoid the damage caused to the body of their children due to excessive drug Yin and Yin Body.