A kind of traditional Chinese medicine prescription and its products for treating hypertension

Abstract

The invention discloses compound traditional Chinese medicine for treating hypertension. The compound traditional Chinese medicine is prepared from the raw materials of rhizoma gastrodiae, uncariae ramulus cum uncis, rhizoma chuanxiong, rauwolfia root, rhizoma pinelliae praeparatum and the like, and the raw materials are extracted and separated by a 0 to 75% ethanol water solution to be prepared into certain dosage forms. The compound traditional Chinese medicine has the effects of suppressing hyperactive liver for calming endogenous wind and eliminating phlegm by cooling and can be applied toprimary hypertension or refractory hypertension liver fire hyperactivity and phlegm heat accumulation patients. Pharmacodynamic study shows that the compound traditional Chinese medicine can obviously reduce systolic pressure and diastolic pressure of spontaneous hypertension and renal hypertension model animals and has a durable blood pressure lowering effect. Clinical research results show thatthe medicine disclosed by the invention can effectively improve all traditional Chinese medicine symptoms of the hypertension liver fire hyperactivity and phlegm heat accumulation patients, can effectively reduce blood pressure of the patient and has no obvious adverse drug reaction. The compound traditional Chinese medicine can be applied to treating hypertension, is safe and effective and has convenience in use; clinical effects and pharmacodynamic study prove that the compound traditional Chinese medicine disclosed by the invention has the functions of suppressing hyperactive liver for calming endogenous wind and eliminating phlegm by cooling and is effective dedicated medicine for treating hypertension.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a compound traditional Chinese medicine for treating hypertension. Background technique [0002] Hypertension is a clinical syndrome characterized by elevated systemic arterial systolic blood pressure (SBP) and / or diastolic blood pressure (DBP). Its high disability rate and death rate have brought serious material and spiritual damage to society and families. In my country, the prevalence rate of people over 15 years old is 11.2%, and the prevalence rate of people over 60 years old is as high as 43.7%. It is estimated that among the 1.3 billion people in my country, the total number of hypertensive patients is about 120 million, and hypertensive patients have lifelong characteristics of medication. [0003] At present, the six major types of drugs used in the treatment of hypertension by western medicine are still the main antihypertensive drugs in clinical applicat...

AI Technical Summary

Problems solved by technology

The patent ZL201010125992.2 authorized by the inventor of the present application also discloses a traditional Chinese medicine composition for treating hypertension, which is made of the following traditional Chinese medicine raw materials in proportions by weight: 1-2 parts of Rhizoma Chuanxiong, 1.5-2 parts of Uncaria, Ophiopogon japonicus 1-1.5 parts, but the effect of this traditional Chinese medicine composition in nourishing yin, softening the liver and calming the wind, promoting blood circulation, dredging the meridian and stopping dizziness, and lasting drug effect still needs to be improved

201410362490X discloses a traditional Chinese medicine composition for treating hypertension, which is made of the following traditional Chinese medicine raw materials in proportions by weight: Uncaria 0.5-2 parts, Rhizoma Chuanxiong 1-2 parts, Angelica sinensis 1-2 parts, Rauwolfia 0-4 parts 0 to 4 parts of Apocynum, can effectively improve various symptoms of traditional Chinese medicine in patients with hypertensive yin deficiency and yang hyperactivity, and blood stasis blocking collaterals. The curative effect still needs to be improved

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