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Transcranial ultrasound cerebral angiography super-resolution imaging method based on Markov chain Monte Carlo multi-object tracking

An imaging method and super-resolution technology, applied in ultrasonic/sonic/infrasound image/data processing, ultrasonic/sonic/infrasonic diagnosis, ultrasonic/sonic/infrasonic Permian technology, etc. Acquisition time, not suitable for speed imaging, etc.

Active Publication Date: 2018-03-06
XI AN JIAOTONG UNIV
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Problems solved by technology

Based on the super-resolution optical wave imaging method, the research team of the Department of Biomedical Engineering of the Technion-Israel Institute of Technology developed a combined microbubble ultrasonic super-resolution imaging method that can be used for high concentration and low acquisition time, but its resolution is lower than that of single microbubble tracking. Method has significant limitations and it is not suitable for velocity imaging of microbubbles / blood flow

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  • Transcranial ultrasound cerebral angiography super-resolution imaging method based on Markov chain Monte Carlo multi-object tracking
  • Transcranial ultrasound cerebral angiography super-resolution imaging method based on Markov chain Monte Carlo multi-object tracking
  • Transcranial ultrasound cerebral angiography super-resolution imaging method based on Markov chain Monte Carlo multi-object tracking

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Embodiment Construction

[0076] The present invention will be described in further detail below in conjunction with the accompanying drawings and embodiments.

[0077] Such as figure 1 As shown, in the example experiment of the present invention, the low-frequency transcranial dedicated ultrasonic linear array transducer emits 5-angle ultrasonic plane waves, receives echo signals and transmits the echo signals to the host under the control of the host of the open ultrasonic imaging system; The echo signal is transmitted to the receiving module of the open ultrasonic imaging system; the receiving module samples and stores the received echo signal as radio frequency sampling data and transmits it to the computer;

[0078] The computer performs echocardiographic ultrasound images on echo radio frequency sampling data, extracts images of contrast microbubbles, removes artifacts, deduces trajectory of contrast microbubbles, and performs super-resolution imaging. Additionally, if figure 1 As shown, contra...

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Abstract

The invention provides a transcranial ultrasound cerebral angiography super-resolution imaging method based on Markov chain Monte Carlo multi-object tracking. The transcranial ultrasound cerebral angiography super-resolution imaging method comprises the following steps: sampling an ultrasound plane wave echo signal received by a low-frequency transcranial dedicated ultrasound linear array energy converter, and converting into radio frequency data; according to the radio frequency data, generating an ultrasound cerebral angiography image; removing background information generated by time domainmedian filtering in the ultrasound cerebral angiography image, and keeping image information of angiography microbubbles; through the Markov chain Monte Carlo multi-object tracking, deducing an angiography microbubble trajectory; according to a trajectory set obtained by deduction, carrying out cerebral angiography super-resolution imaging. The invention puts forward the transcranial super-resolution imaging method based on Markov chain Monte Carlo. Compared with other super-resolution imaging methods, the transcranial super-resolution imaging method disclosed by the invention has the characteristics of high frame rate, low data acquisition amount and suitability for high-concentration angiography microbubbles. Compared with traditional low-frequency angiography imaging, the method disclosed by the invention is characterized in that a cerebral vascular resolution ratio can be greatly improved under a noninvasive condition.

Description

technical field [0001] The invention belongs to the technical field of ultrasonic detection and ultrasonic imaging, and relates to a Markov chain Monte Carlo multi-target tracking algorithm combined with contrast microbubbles, in particular to transcranial ultrasound cerebral angiography based on Markov chain Monte Carlo multi-target tracking Super-resolution imaging methods. Background technique [0002] Transcranial ultrasound has become a hot field of ultrasound research in recent years. In terms of diagnosis and treatment, ultrasound combined with contrast-enhanced microbubbles has been proven to be a new method for the diagnosis of cerebrovascular diseases, the treatment of cerebral thrombosis, or the opening of the blood-brain barrier. The brain endothelial cells of the barrier are separated, so that the drug can effectively pass through the intercellular space and reach the target position, realizing non-invasive treatment; and in terms of thrombotic diseases, ultras...

Claims

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Application Information

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IPC IPC(8): A61B8/08
CPCA61B8/0808A61B8/0891A61B8/5207A61B8/5215A61B8/5269
Inventor 万明习柏晨纪美伶张馨予
Owner XI AN JIAOTONG UNIV
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