Medical hydrocolloid dressing and preparation method thereof

A technology of hydrocolloid and hydrocolloid layer, applied in dressings, viscous dressings, medical science, etc., can solve problems such as unreachable, no anti-adhesion antibacterial effect, and inability to use exudate, so as to avoid secondary damage and prevent scarring The effect of strong proliferation and exudative ability

Inactive Publication Date: 2018-05-15
GUANGZHOU RAINHOME PHARM&TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, traditional hydrocolloid dressings generally cannot be used for wounds with more exudate, and have no anti-adhesion and antibacterial effects, and cannot meet the ideal clinical dressing standards

Method used

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  • Medical hydrocolloid dressing and preparation method thereof
  • Medical hydrocolloid dressing and preparation method thereof
  • Medical hydrocolloid dressing and preparation method thereof

Examples

Experimental program
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Effect test

preparation example Construction

[0059] The invention provides a kind of preparation method of medical hydrocolloid dressing, comprising:

[0060] A) mixing silica gel, sodium carboxymethylcellulose, pectin, gelatin, sodium polyacrylate and organic silicon quaternary ammonium salt, and stirring to obtain a reaction solution;

[0061] B) transferring the reaction solution into a mold provided with a waterproof membrane, solidified to obtain a semi-finished product;

[0062] C) adhering the semi-finished product to a barrier film to obtain a medical hydrocolloid dressing.

[0063] According to the preparation method of the medical hydrocolloid dressing provided by the invention, silica gel, sodium carboxymethyl cellulose, pectin, gelatin, sodium polyacrylate and organic silicon quaternary ammonium salt are mixed and stirred to obtain a reaction solution.

[0064] The silicone gel of the present invention is well known to those skilled in the art, and is divided into silicone gel A and silicone gel B. When in u...

Embodiment 1

[0077] A preparation method of medical hydrocolloid dressing, comprising the following steps

[0078] Step A: Cut the silicone mold to the size of the mold, put it into the forming groove mold, which is coated with a layer of Teflon.

[0079] Step B: Mix 15g of silicone gel A and 15g of silicone gel B, and stir for 5 minutes. After mixing evenly, add 10g of sodium carboxymethylcellulose, 10g of pectin, 5g of gelatin, and 5g of sodium polyacrylate in sequence, and stir After 20 minutes, 1 g of organosilicon quaternary ammonium salt was finally added, and the stirring was continued for 15 minutes. All the stirring was carried out under normal temperature and vacuum.

[0080] Step C: Pour the reaction solution in step B into the mold in step A, let it stand at room temperature for 15 minutes, put it in an oven at 90°C, and let it solidify for 3 hours. After it is completely cured, take out the sample

[0081] Step D: Paste the sticky side of the sample in step C with a barrier f...

Embodiment 2

[0083] Step A: Cut the PU film to the size of the mold, put it into the forming groove mold, where the mold is coated with a layer of Teflon.

[0084] Step B: Mix silicone gel 20gA and silicone gel 18gB, stir for 3 minutes, add 20g sodium carboxymethylcellulose, 15g pectin, 8g gelatin, 8g sodium polyacrylate in sequence after mixing evenly, and stir for 15 minutes, Finally, 2 g of organosilicon quaternary ammonium salts were added, and the stirring was continued for 20 min, and all the stirring was carried out under normal temperature and vacuum.

[0085] Step C: Pour the reaction solution in step B into the mold in step A, let it stand at room temperature for 10 minutes, put it in an oven at 100°C, and let it solidify for 2 hours. After it is completely cured, take out the sample

[0086] Step D: Paste the sticky side of the sample in step C with a barrier film, align with the sample and paste to obtain a medical hydrocolloid dressing.

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Abstract

The invention provides a medical hydrocolloid dressing. The medical hydrocolloid dressing comprises a waterproof membrane, a hydrocolloid layer arranged on the waterproof membrane, and an isolation layer arranged on the hydrocolloid layer, wherein the hydrocolloid layer is prepared from the following components: 25 to 40 parts of silica gel; 10 to 30 parts of sodium carboxymethylcellulose, 10 to 20 parts of pectin, 5 to 12 parts of gelatin, 5 to 10 parts of sodium polyacrylate, and 1 to 3 parts of organosilicon quaternary ammonium salt. By selecting the waterproof membrane as a base material,the medical hydrocolloid dressing has the characteristics of transparency, air permeability, water resistance, bacteria barrier and the like. The dressing hydrocolloid layer is prepared from the silica gel, the sodium carboxymethylcellulose, the pectin, the gelatin, the sodium polyacrylate and the organosilicon quaternary ammonium salt in a given ratio, the prepared medical hydrocolloid dressing continuously releases silicone oil when in use so as to soften a wound, thereby achieving an effect for preventing binding of a wound and avoiding the secondary injury. The dressing is high capacity for absorbing seepage and can provide an environment for accelerating the healing of the wound.

Description

technical field [0001] The invention relates to the technical field of medical dressings, in particular to a medical hydrocolloid dressing and a preparation method thereof. Background technique [0002] Hydrocolloid medical dressing is a new type of dressing with the advantages of waterproof, anti-adhesion, moisturizing and heat preservation. At present, the materials and efficacy of hydrocolloid medical dressings are very different. The wounds treated by hydrocolloid dressings are also varied. For different wounds, hydrocolloid medical dressings with good safety and different functions are required. [0003] The hydrocolloid dressing disclosed in the prior art is a medical dressing prepared by blending water-absorbing polymer particles and hot-melt pressure-sensitive adhesive. This dressing combines the adhesive properties of rubber materials with the water-absorbing properties of absorbent polymer materials. The rubber substrate can make the dressing stick to the wound, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/60A61L15/42A61L15/20A61L15/46A61L15/28A61L15/24A61L15/32A61L15/26A61L15/44A61F13/02
CPCA61L15/20A61L15/24A61L15/26A61L15/28A61L15/32A61L15/42A61L15/44A61L15/46A61L15/60A61F13/0213A61F13/0289A61L2300/208A61L2300/418A61L2300/412A61L2300/252A61L2300/404A61L2300/232C08L1/286C08L5/06C08L33/02C08L89/00C08L83/04
Inventor 赵澎黄海燕车七石刘少辉
Owner GUANGZHOU RAINHOME PHARM&TECH CO LTD
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