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Toothpaste and preparation method thereof

A technology of toothpaste and compound enzyme preparation, which is used in dentistry, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve the problems of difficult to determine the dosage of use, single function of enzyme-containing toothpaste, etc.

Inactive Publication Date: 2018-05-29
深圳市芭格美生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The embodiment of the present invention provides a toothpaste, which aims to solve the problem that the dosage of existing fluoride-containing toothpaste for caries prevention and treatment is difficult to determine and the existing enzyme-containing toothpaste has a single function

Method used

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  • Toothpaste and preparation method thereof
  • Toothpaste and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0081] A toothpaste formula, by weight, comprises the following components: anionic surfactant (sodium lauroyl sarcosinate LS-30 3%); compound enzyme preparation (glucanase 0.05%, glucose oxidase 0.05%, lysozyme Enzyme 0.1%, protease 0.1%, amylase 0.1%, pineapple enzyme 0.1%), a total of 0.5%; grinding agent (calcium carbonate 28%, hydrated silica 1.5%, sodium pyrophosphate 3.5%), a total of 33%; moisturizing agent ( Glycerin 40%); thickener (xanthan gum 0.15%, cellulose gum 0.7%), a total of 0.85%; preservatives (paraben 0.2%); pH regulator (citric acid 0.2%); flavoring agent (sodium saccharin 0.3%); essence 0.25%; the balance is deionized water.

[0082] In an embodiment of the present invention, the preparation method of toothpaste, comprises the steps:

[0083] Step 1: Weigh each component according to the above toothpaste formula and set aside.

[0084] Step 2: Add part of deionized water into the batching pot, preferably, add 15%-20% (weight ratio) of deionized water i...

Embodiment 2

[0089] A toothpaste formula, by weight, comprises the following components: anionic surfactant (sodium lauroyl sarcosinate LS-30 5%); compound enzyme preparation (dextranase 0.1%, glucose oxidase 0.1%, lysozyme Enzyme 0.1%, protease 0.3%, amylase 0.3%, pineapple enzyme 0.1%), a total of 1%; abrasives (calcium carbonate 28%, hydrated silica 1.5%, sodium pyrophosphate 2.5%), a total of 32%; moisturizing agent ( Glycerin 35%); thickener (xanthan gum 0.15%, cellulose gum 1%), a total of 1.15%; preservatives (paraben 0.5%); pH regulator (citric acid 0.2%); flavoring agent (sodium saccharin 0.5%); essence 0.25%; the balance is deionized water.

[0090] In the embodiment of the present invention, the preparation method of toothpaste is identical with embodiment 1.

Embodiment 3

[0092] A toothpaste formula, by weight, comprises the following components: anionic surfactant (sodium lauroyl sarcosinate LS-30 5%); compound enzyme preparation (dextranase 0.2%, glucose oxidase 0.2%, lysozyme Enzyme 0.2%, protease 0.3%, amylase 0.3%, pineapple enzyme 0.3%), a total of 1.5%; grinding agent (calcium carbonate 25%, hydrated silica 2.5%, sodium pyrophosphate 3.5%), a total of 31%; moisturizing agent ( Glycerin 40%); thickener (xanthan gum 0.2%, cellulose gum 0.7%), a total of 0.9%; preservatives (paraben 0.5%); pH regulator (citric acid 0.1%); flavoring agent (sodium saccharin 0.3%); essence 0.15%; the balance is deionized water.

[0093] In the embodiment of the present invention, the preparation method of toothpaste is identical with embodiment 1.

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Abstract

The invention is applicable to the technical field of oral cavity health-care articles and provides toothpaste and a preparation method thereof. The toothpaste is prepared from the following components in percentage by weight: 3 percent to 5 percent of an anionic surfactant, 0.5 percent to 1.5 percent of a compound enzyme preparation, 30 percent to 35 percent of a grinding agent, 35 percent to 45percent of a humectant, 0.25 percent to 0.9 percent of a thickener, 0.2 percent to 0.5 percent of a preservative, 0.1 percent to 0.2 percent of a pH (Potential of Hydrogen) regulator and the balance of de-ionized water, wherein the compound enzyme preparation is a mixture of at least five of glucanase, glucose oxidase, polyphenol oxidase, lysozyme, coenzyme Q10, amylase, pancreatin, catalase, bromelain and proteinase. The toothpaste provided by the invention does not contain fluorine and adopts food-grade raw materials, so that the product has high safety, is environmentally friendly and easyto degrade and has no toxin and no residues; the enzyme activity stability of the compound enzyme preparation in a formula system is high; the toothpaste can be used for effectively enhancing the decayed tooth prevention capability, also can be used for effectively alleviating the gingival bleeding symptom; meanwhile, the toothpaste has the effects of sterilizing and diminishing inflammation, whitening teeth and refreshing breath.

Description

technical field [0001] The invention belongs to the technical field of oral health products, in particular to a toothpaste and a preparation method thereof. Background technique [0002] Among oral diseases, dental caries and periodontal disease are the main causes of tooth loss. The etiology of the two oral diseases is relatively complicated. It is generally believed that caries is mainly caused by bacterial infection. Dental plaque is one of the important factors causing caries. There are many cocci on the surface of dental plaque, which are composed of brevibacteria and food residues. Thickness varies. Cariogenic Streptococcus mutans can produce glucan. Dextran is a viscous colloidal substance. The more important polysaccharides in plaque are dextran and fructose, which serve as a matrix to gather bacteria and oral residues to corrode the tooth surface. [0003] Fluoride has been widely used in most toothpaste as an anti-caries active substance. A large number of clini...

Claims

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Application Information

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IPC IPC(8): A61K8/66A61K8/35A61Q11/00A61P1/02A61P7/04
CPCA61K8/66A61K8/355A61K2800/30A61K2800/5922A61K2800/596A61Q11/00
Inventor 郭宏涛董荣生
Owner 深圳市芭格美生物科技有限公司
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