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Chinese herbal medicine compound composition for inhibiting avian influenza virus H9N2

A technology of avian influenza virus and Chinese herbal medicine, applied in the field of livestock and poultry breeding, can solve the problems of unavailable products and achieve excellent inhibitory effect

Inactive Publication Date: 2018-06-15
FOSHAN UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] However, how to apply the above-mentioned Chinese herbal medicine to the medicament for inhibiting the H9N2 avian influenza virus is of great significance to the development of the industry, and there is still no ideal product on the market

Method used

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  • Chinese herbal medicine compound composition for inhibiting avian influenza virus H9N2
  • Chinese herbal medicine compound composition for inhibiting avian influenza virus H9N2

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] A compound composition of Chinese herbal medicine for suppressing H9N2 avian influenza virus, the medicinal active ingredients of the medicinal ingredients include 20 parts of Mianma Guanzhong, 20 parts of honeysuckle, 20 parts of forsythia, 20 parts of skullcap, 20 parts of licorice and 20 parts of licorice Radix isatidis, the ingredients of the raw materials are mixed to obtain the Chinese herbal compound composition of Example 1.

Embodiment 2

[0018] A compound composition of Chinese herbal medicine for suppressing H9N2 avian influenza virus, the medicinal active ingredients of which, in parts by weight of raw materials, comprise 20 parts of Mianma Guanzhong, 20 parts of honeysuckle, 20 parts of forsythia, 20 parts of skullcap, 20 parts of licorice, 20 parts of licorice Radix Isatidis, 15 parts of Inverted Grass, 15 parts of Eucalyptus vulgaris, 15 parts of Shuidongge, 15 parts of Polygonum cuspidatum, 15 parts of Shandougen and 15 parts of Daqingye, the ingredients of the raw materials are mixed uniformly to obtain the Chinese herbal medicine compound of Example 2 combination.

Embodiment 3

[0019] Example 3: Test

[0020] 1. Preparation of test liquid

[0021] Get the Chinese herbal medicine compound composition obtained in Example 1 and Example 2 to make test liquid 1 and test liquid 2 respectively, and the specific operation method is as follows:

[0022] 1) Take the Chinese herbal medicine compound composition, add 10 times of distilled water, soak for 10 minutes, heat to boiling, boil at 80-90°C for 2 hours, let stand to room temperature, filter with gauze to obtain filtrate;

[0023] 2) Concentrate the obtained filtrate with a spiral evaporator to a concentration of 1 g / ml of the original drug, centrifuge at high speed for 15 min under the condition of 8000 r / min, take the supernatant and place it in a -20°C freezer for freezing for 12 hours to obtain a frozen liquid;

[0024] 3) Thaw the frozen liquid, place it in a centrifuge tube and ultracentrifuge it for 15 minutes under the condition of 10000r / min, take the supernatant and dispense it into a 10ml EP t...

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PUM

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Abstract

The invention discloses a Chinese herbal medicine compound composition for inhibiting an avian influenza virus H9N2. The pharmaceutical effective ingredients comprise rhizoma dryopteris crassirhizomae, honeysuckle, fructus forsythia, scutellaria baicalensis, liquorice and isatis root. The Chinese herbal medicines are specially compounded, so that the compound composition shows an excellent effectof inhibiting the avian influenza virus H9N2 after being applied to the avian influenza virus H9N2, and is particularly suitable for the daily use in feeding of livestock and poultry at the same time.

Description

technical field [0001] The invention relates to the field of livestock and poultry feeding, in particular to a livestock and poultry feed additive. Background technique [0002] In recent years, relevant scholars have conducted many studies on the anti-influenza virus of traditional Chinese medicine, and there are also similar anti-influenza virus formulations, such as Lianhua Qingwen Granules, whose formulations are composed of Forsythia, Zhimahuang, Honeysuckle, Almond, Mint, Mianma Guanzhong , Rhodiola, gypsum, patchouli and other drugs. Lianhua Qingwen Granules is a modern traditional Chinese medicine compound preparation for the treatment of influenza developed by Professor Wu Yiling, and is currently widely used in the treatment of influenza. [0003] Mianma Guanzhong, Xu Cheng et al. used chicken embryo in vitro antiviral experiments to explore the effect of three extracts of Mianma Guanzhong against mouse pneumovirus FM1 strain. FM1 strain has direct inhibitory eff...

Claims

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Application Information

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IPC IPC(8): A61K36/634A61K36/704A61K36/855A61P31/16
CPCA61K36/12A61K36/185A61K36/195A61K36/21A61K36/315A61K36/355A61K36/484A61K36/489A61K36/539A61K36/634A61K36/704A61K36/855A61K2300/00
Inventor 张济培李荣旭陈济铛何钢华张溢珊陈建红
Owner FOSHAN UNIVERSITY
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