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Soft capsule liquid capable of retarding aging of rubber, soft capsules, prostate capsules and preparation methods thereof

A technology of soft capsules and rubber skins, which is applied in the direction of capsule delivery, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., which can solve problems such as not being able to meet the needs of prostatitis drugs, and achieve improved stability, Improve the effect of curative effect

Inactive Publication Date: 2018-06-29
广东广发制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But the sustained-release profile of the existing soft capsules can not well meet the demand for prostatitis drugs

Method used

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  • Soft capsule liquid capable of retarding aging of rubber, soft capsules, prostate capsules and preparation methods thereof
  • Soft capsule liquid capable of retarding aging of rubber, soft capsules, prostate capsules and preparation methods thereof
  • Soft capsule liquid capable of retarding aging of rubber, soft capsules, prostate capsules and preparation methods thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0052] A kind of soft capsule liquid that delays rubber aging, described soft capsule liquid comprises the raw material of following weight portion:

[0053]

[0054] Wherein, the sunscreen is titanium dioxide, and the preservative is ethylparaben.

Embodiment 2

[0056] A kind of soft capsule liquid that delays rubber aging, described soft capsule liquid comprises the raw material of following weight portion:

[0057]

[0058] Wherein, the sunscreen is titanium dioxide, and the preservative is ethylparaben.

Embodiment 3

[0060] A kind of soft capsule liquid that delays rubber aging, described soft capsule liquid comprises the raw material of following weight portion:

[0061]

[0062]

[0063] Wherein, the sunscreen is titanium dioxide, and the preservative is ethylparaben.

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PUM

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Abstract

The invention relates to the technical field of soft capsules, in particular to a soft capsule liquid capable of retarding aging of rubber, soft capsules, prostate capsules and preparation methods thereof. The soft capsule liquid is prepared from gelatin, glycerin, sorbitol, pigments, a light-screening agent, a preservative and water. Aging of rubber of the prepared soft capsules is retarded, theindexes of glue ball disintegration time limit, dissolution and the like meet requirements within the shelf life, the stability and shelf life of traditional Chinese medicinal soft capsules are enhanced and prolonged, and the disintegration stability can be up to 24 months. The invention further provides prostate capsules matched with the soft capsules. The prostate capsules have the effects of clearing heat to promote diuresis, activating blood, removing stasis, dredging collaterals and regulating menstruation. As shown by modern pharmacodynamical research experiments, the soft capsules and the prostate capsules can be used for treating various prostatitis, and are especially suitable for chronic prostatitis.

Description

technical field [0001] The invention relates to the technical field of soft capsules, in particular to a soft capsule liquid for delaying rubber aging, a soft capsule, a Qianlie capsule and a preparation method thereof. Background technique [0002] The characteristics of the dosage form of the soft capsule determine that the drug in the capsule shell is isolated from the outside world, and its appearance, disintegration and dissolution, stability and other quality indicators are all affected by the material of the capsule shell; at the same time, the composition and properties of the drug in the capsule It also affects the stability of the capsule shell. The traditional soft capsule rubber formula is composed of gelatin, glycerin, water, titanium dioxide, ethylparaben and pigments, etc. During storage, the rubber is easily oxidized into aldehydes, forming a thin film, making it difficult for the capsule to dissolve. [0003] At the same time, the soft capsule has plasticit...

Claims

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Application Information

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IPC IPC(8): A61K9/48A61K36/86A61K47/10A61P13/08
CPCA61K9/4816A61K9/4825A61K36/232A61K36/287A61K36/288A61K36/31A61K36/324A61K36/328A61K36/344A61K36/355A61K36/36A61K36/486A61K36/66A61K36/78A61K36/84A61K36/86A61K2300/00
Inventor 高东翔周树和黄芳勇刘建豪张东梅
Owner 广东广发制药有限公司
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