Unlock instant, AI-driven research and patent intelligence for your innovation.

Rare-earth-doped hydroxyapatite nano-material and preparation method thereof

A hydroxyapatite and rare earth doping technology is applied in the field of rare earth doped hydroxyapatite nanomaterials and their preparation, which can solve the problems of weak bacteriostatic effect and the like, and achieve the effect of good biocompatibility

Inactive Publication Date: 2018-07-06
浙江美加华医疗技术有限公司
View PDF0 Cites 7 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although rare earth ions have been proved to have antibacterial effect, their antibacterial effect is not strong, and their synergistic effect after hybridization or coordination with other compounds can greatly improve their antibacterial properties

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Rare-earth-doped hydroxyapatite nano-material and preparation method thereof
  • Rare-earth-doped hydroxyapatite nano-material and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Example 1: 10% mol ratio rare earth lanthanum doped hydroxyapatite nanomaterial

[0020] The Ca(NO3) of 10mL 0.01mol / L concentration Aqueous solution and the La(NO3) of 10ml 0.001mol / L concentration Aqueous solution while stirring join in the aqueous solution (0.02mol / L), after stirring at room temperature for 3 hours, add 10mL (NH4)2HPO4 (0.006mol / L) aqueous solution while stirring, adjust the pH value to 10 with 0.05mol / L ammonia water, then transfer the mixed solution into 36mL React in an autoclave at 150°C for 10 hours, take out the crystals after cooling, wash with deionized water, and dry at 60°C to obtain the final sample.

Embodiment 2

[0021] Example 2: 1% mol ratio rare earth lanthanum doped hydroxyapatite nanomaterial

[0022] The Ca(NO3) aqueous solution of 10mL 0.01mol / L concentration and the La(NO3) aqueous solution of 1ml 0.001mol / L concentration join while stirring in the aqueous solution (0.02mol / L), after stirring at room temperature for 3 hours, add 10mL (NH4)2HPO4 (0.006mol / L) aqueous solution while stirring, adjust the pH value to 10 with 0.05mol / L ammonia water, then transfer the mixed solution into 36mL React in an autoclave at 150°C for 10 hours, take out the crystals after cooling, wash with deionized water, and dry at 60°C to obtain the final sample.

Embodiment 3

[0023] Example 3: 20% mol ratio rare earth lanthanum doped hydroxyapatite nanomaterial

[0024] The Ca(NO3) aqueous solution of 10mL 0.01mol / L concentration and the La(NO3) aqueous solution of 20ml 0.001mol / L concentration are joined in the aqueous solution (0.02mol / L), after stirring at room temperature for 3 hours, add 10mL (NH4)2HPO4 (0.006mol / L) aqueous solution while stirring, and adjust the pH value to 10 with 0.05mol / L ammonia water, then transfer the mixed solution to 36mL React in an autoclave at 150°C for 10 hours, take out the crystals after cooling, wash with deionized water, and dry at 60°C to obtain the final sample.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention especially relates to a rare-earth-doped hydroxyapatite nano-material applied to bone repair and dental restoration and a preparation method thereof, belonging to the field of artificialbones and dental materials.

Description

technical field [0001] The invention relates to the field of artificial bones and dental materials, in particular to a rare earth-doped hydroxyapatite nanometer material and a preparation method thereof for bone repair and dental repair. Background technique [0002] Hydroxyapatite (Hydroxyapatite, HAP) is the main component of vertebrate bones and teeth. For example, the mass fraction of HAP in human bone accounts for about 60%, and the mass fraction of HAP on the enamel surface of human teeth accounts for more than 95%. Human bone is mainly composed of organic bone matrix structure and inorganic bone salt framework structure. The basic unit of inorganic structure is needle-shaped and columnar apatite crystals, which are about 40-60nm long, 20nm wide, and 3-5nm thick. Synthetic hydroxyapatite has good bioaffinity, biocompatibility, bioactivity and osteoconduction, and is an excellent hard tissue replacement material. However, due to the inherent brittleness and low toughne...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C01B25/32B82Y40/00
CPCC01B25/32C01P2002/72C01P2004/04C01P2004/64
Inventor 顾凤龙
Owner 浙江美加华医疗技术有限公司
Features
  • R&D
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com