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Active substance having continuous pressure-reduction function and preparation method and application thereof

A technology of active substances and functions, applied in the field of active substances with continuous antihypertensive function and its preparation, achieving low cost, good clinical application prospects, and less side effects

Inactive Publication Date: 2018-07-10
南京博彩生物工程有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there is no literature report that Xiangqi Jiangya Granules have a sustained antihypertensive effect.

Method used

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  • Active substance having continuous pressure-reduction function and preparation method and application thereof
  • Active substance having continuous pressure-reduction function and preparation method and application thereof
  • Active substance having continuous pressure-reduction function and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0048] Recipe: dry banana peel 1050g, add appropriate amount of auxiliary materials.

[0049] Preparation Process:

[0050]1. Take the skin of ripe bananas with pockmarks, dry the skin in an oven at 60-80 degrees, and crush it into coarse powder. Take 1050g of the above powder in a container, add 5000ml of water, heat to boil, keep boiling slightly for 30-40 minutes, filter, take the supernatant, concentrate to 100ml, and set aside; or after the supernatant is properly concentrated, it is spray-dried / freeze-dried to obtain dry powder.

[0051] 2. Take the above-mentioned concentrated solution of banana peel or dried powder of the concentrated solution (equivalent to 1050g of dry banana peel, 30 grams per day, edible for 35 days) and add auxiliary materials, go through sieving, mixing, granulating, drying and tableting. Tablets (280 tablets, once a day in the morning and evening, 4 tablets each time); or sieved, mixed, granulated, dried, and made into capsules (280 tablets, o...

Embodiment 2

[0053] Recipe: dry banana peel 1050g, add appropriate amount of auxiliary materials.

[0054] Preparation Process:

[0055] 1. Take the skin of ripe bananas with pockmarks, dry the skin in an oven at 60-80 degrees, and crush it into coarse powder. Take 1050g of the above powder in the container, add 5000ml of boiling water, soak for 30-40 minutes, filter, and take the supernatant; add 5000ml of boiling water to the filter residue, extract twice in the same way, filter again, and take the supernatant. The two extracts are combined and concentrated to 500ml; or the supernatant is properly concentrated and spray-dried / freeze-dried to make a powder.

[0056] 2. Take the above-mentioned banana peel concentrate (equivalent to 1050g of dry banana peel, 30 grams per day, edible for 35 days), add honey 2g, xanthan gum 0.16g, glyceryl monostearate 0.16g, carrageenan 0.16g, citric acid 0.4g, add water to 700ml, stir and mix evenly, fill into 10ml / bottle of oral liquid, seal, cap, and s...

Embodiment 3

[0058] Recipe: dry banana peel 1050g, add appropriate amount of auxiliary materials

[0059] Preparation Process:

[0060] 1. Take the skin of ripe bananas with pockmarks, dry the skin in an oven at 60-80 degrees, and crush it into coarse powder. Take 1050g of the above powder in a container, add 5000ml of water, heat to boil, keep boiling slightly for 30-40 minutes, filter, take the supernatant, concentrate it properly and spray dry / freeze dry to obtain dry powder.

[0061] 2. Take the concentrated solution and dry it into powder (equivalent to 1050g of dry banana peel, 30 grams per day, edible for 35 days), take an appropriate amount of tea leaves and grind them into tea powder, add an appropriate amount of milk powder, mix the dried powder with tea powder and The milk powder is mixed evenly, and packed to obtain a banana peel solid drink (70 bags, each bag of 15g of crude drug, one bag in the morning and one in the evening).

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Abstract

The invention belongs to the fields of food, health food and drug preparation, and relates to an active substance having a continuous pressure-reduction function and a preparation method and an application thereof. The active substance is banana peel, and especially a banana peel extract, the banana peel extract is obtained by the steps that the banana peel is dried and crushed, water is added fordecocting or immersing, the material is filtered, a supernatant is taken, and the material is subjected to proper condensation to a concentrate or condensation and drying to obtain the powder. The active substance has the continuous pressure-reduction function, the blood pressure can keep a low level in 12 days after drug withdrawal, the active substance takes the banana peel as a main raw material, cost is low, side effect is less, and the active substance has good clinical application prospect.

Description

technical field [0001] The invention belongs to the field of food, health food and medicine preparation, and relates to an active substance with the function of continuously lowering blood pressure and its preparation method and application, in particular to an active substance with the function of continuously lowering blood pressure with banana peel as the main raw material And its preparation method and application. Background technique [0002] Hypertension is a common and frequently-occurring disease. According to an article published in the "American Journal of Hypertension" on April 3, 2014, the prevalence of hypertension in my country is 29.6%, and the prevalence rate of men is higher than that of women (31.2% vs 28. 0%), the awareness rate, treatment rate and control rate were 42.6%, 34.1% and 9.3% respectively, and the blood pressure compliance rate of patients receiving antihypertensive treatment was 27.4%. Multiple lifestyle factors are associated with the develo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/88A61P9/12A23L33/00A61K131/00
CPCA23L33/00A23V2002/00A61K36/88A61K2236/331A61K2236/39A23V2200/326
Inventor 柯学郭青龙赵丽冯锋高源郭永健
Owner 南京博彩生物工程有限公司
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