Versatile plasma purification system based on centrifugal separation plasma method

Abstract

The invention discloses a versatile plasma purification system based on a centrifugal separation plasma method. The system comprises a plasma replacement device, a plasma dialysis filtration adsorption device and a plasma transfer device, the plasma replacement device comprises a centrifugal plasma separator, the plasma transfer device comprises a plasma transfer bag and a discard plasma bag, a plasma transfer pipeline is arranged between the plasma output end of the plasma replacement device and the plasma transfer bag, a plasma discharge pipeline is disposed between the plasma transfer bag and the discard plasma bag, and a plasma circulation pipeline is disposed between the output end of the plasma dialysis filtration adsorption device and the plasma discharge pipeline. The plasma purification system fully exerts the advantages of centrifugal plasma replacement, plasma dialysis filtration and plasma double adsorption treatment, meets the requirements of centrifugal plasma replacement, plasma dialysis filtration and plasma adsorption for different plasma flow velocities, and has the advantages of more comprehensive functions, wider application ranges and the like.

Description

Technical field [0001] The present invention relates to a medical instrument for blood purification, in particular to a versatile plasma purification system (VPPS) based on a centrifugal plasma separation method. Background technique [0002] Acute liver failure or chronic acute liver failure is severe and progressing rapidly, and is prone to multiple organ failure. If the disease cannot be prevented from progressing in the short term, it will be life-threatening and urgent liver transplantation is required. There are a lot of toxins in patients with acute or chronic liver failure, accompanied by coagulation dysfunction, and patients with advanced liver failure have more serious bleeding tendency. Artificial liver is a blood purification method used to treat liver failure. At present, there are four basic artificial liver methods at home and abroad: plasma exchange, plasma adsorption, hemodialysis and hemofiltration. Artificial liver treatment for patients with severe liver fai...

AI Technical Summary

Problems solved by technology

However, it can only operate on the basis of membrane plasma separation, and is not suitable for patients with advanced liver failure with poor coagulation function

Moreover, the plasma velocity during plasma adsorption and filtration is 25-30ml / min, and the ability to remove water-soluble toxins is insufficient

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