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Positioning marker made of degradable metal and method for preparing positioning marker

A technology for positioning markers and markers, applied in the direction of diagnostic markers, echo/ultrasonic imaging agents, X-ray contrast agent preparation, etc., can solve the problems of patients with foreign body sensation and moving to other parts, so that it is not easy to fall off or shift, and it is not easy to Displacement, biocompatibility enhancement effect

Pending Publication Date: 2018-08-10
西安卓恰新材料科技有限公司
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Problems solved by technology

[0006] In order to solve the problem that the existing positioning markers are made of non-degradable metal or alloy materials, which may bring foreign body sensation to patients, and may also move to other parts, and even require a second operation to remove the markers, bringing potential risks and risks to patients. Hidden dangers, the main purpose of the present invention is to provide a positioning marker made of degradable metal and its preparation method. The positioning marker is made of pure magnesium or magnesium alloy, wherein the total content of impurities in the magnesium alloy is less than 0.01 % mass fraction, the positioning marker is at least braided by three magnesium wires to form a positioning end, the positioning marker can be fixed inside the human body with the positioning end, and gradually degrades over time, absorbed by surrounding tissues or metabolized out of the human body without secondary Surgical removal

Method used

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  • Positioning marker made of degradable metal and method for preparing positioning marker
  • Positioning marker made of degradable metal and method for preparing positioning marker
  • Positioning marker made of degradable metal and method for preparing positioning marker

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[0027] In order to be able to understand the technical features and practical effects of the present invention in detail, and to implement them according to the contents of the description, the preferred embodiment as shown in the accompanying drawings is further described in detail as follows, please refer to the first preferred embodiment. figure 1 The illustrated positioning marker made of degradable metal includes a marker body 10A.

[0028] The length of the marker body 10A is 10-20 mm, and the diameter of the outermost edge is 1-3 mm. The marker body 10A is a long strip structure made of at least three magnesium wires made of pure magnesium wire or magnesium alloy. , preferably, the diameter of each magnesium wire is 0.5 mm to 0.8 mm.

[0029] One end of the marker body 10A forms a winding end 11A that is intertwined with each other, and the winding end 11A can be in contact with a push rod in a puncture needle sleeve, and a positioning end that is separated from each ot...

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Abstract

The invention relates to a positioning marker made of degradable metal and a method for preparing the positioning marker. The positioning marker is made of pure magnesium or magnesium alloy. The totalcontent of impurities in the pure magnesium and the magnesium alloy is lower than 0.01% by mass fraction. At least three magnesium wires are woven to obtain the positioning marker. The positioning marker is provided with a wound end and a positioning end. The positioning end is connected to the wound end and is of a claw-shaped or anchor-shaped structure. The positioning marker and the method have the advantages that the tensile strength of the positioning marker is higher than 200 megapascal, the percentage elongation after fracture is higher than 10%, and the in-vivo degradation rate is lower than 0.5 mm / year; the positioning marker can be developed in ultrasonic and X rays, the locations of the positioning marker can be detected by the aid of ultrasonic or molybdenum target X rays in operative procedures and postoperative treatment procedures, and the positioning marker can be gradually degraded along with postoperative treatment, and can be absorbed by surrounding tissues or discharged from human bodies by means of metabolism without being taken out by means of second operation.

Description

technical field [0001] The invention relates to a positioning marker related to preoperative biopsy, intraoperative resection and postoperative treatment of breast tissue during the treatment of breast tumors, in particular to a positioning marker made of degradable metal and a preparation method thereof. Background technique [0002] Breast minimal lesions are small and clinically inaccessible. Precise positioning is required for marking after biopsy sampling, during surgery, and postoperative treatment to avoid surgical resection of too much normal tissue while ensuring the accuracy of diagnosis and treatment. [0003] The currently used positioning marker material is generally titanium, titanium alloy or stainless steel. For breast tumors that require surgical resection, the markers will be removed along with the lesion and part of the normal tissue. For patients who do not need surgery after postoperative treatment or biopsy, the markers will remain in the body for a lo...

Claims

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Application Information

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IPC IPC(8): A61B90/00A61K49/04A61K49/22
CPCA61K49/04A61K49/22A61B90/39A61B2090/3991A61B2090/3966A61B2090/3908
Inventor 展京美益明星王颖肖杰
Owner 西安卓恰新材料科技有限公司
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