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Extraction method of ginsenoside

A technology of ginsenosides and extraction methods, which is applied in the direction of medical formulas, medical preparations containing active ingredients, plant raw materials, etc., can solve the problems of cumbersome operation, long extraction time, waste of medicinal materials, etc., and achieve increased extraction content and high extraction efficiency , the effect of high added value

Inactive Publication Date: 2018-08-10
佛山市飞程信息技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the existing methods for extracting ginsenosides from ginseng still have disadvantages such as cumbersome operation, long extraction time, low efficiency, insufficient extraction of active ingredients, and waste of medicinal materials.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] 1) Microbial treatment: Wash and slice ginseng, then add equal weight of distilled water and stir evenly, and homogenize under high pressure for 1 to 3 hours to obtain a homogenate, add Lactobacillus acidophilus to the homogenate, and ferment in a room at 35°C 35 hours;

[0022] 2) Supercritical extraction: import the fermented liquid into the extraction kettle, start the supercritical device, CO 2 The gas is filtered through the filter at a flow rate of 20L / h, and then pumped into the extraction tank by the compressor until the set pressure is 35MPa. The extraction temperature is controlled by the circulating water in the jacket of the extraction tank and stabilized at 35°C. At the same time, beeswax is introduced as an entrainer , at an extraction temperature of 35°C, a fluid pressure of 35MPa, and a flow rate of 0.3ml / min, extract for 3h to obtain the extract, CO 2 After the fluid extract reaches the separation tank to depressurize, it is separated from the extract,...

Embodiment 2

[0027] 1) Microbial treatment: wash and slice the ginseng, then add equal weight of distilled water and stir evenly, homogenate under high pressure for 3 hours to obtain a homogenate, add Lactobacillus casei to the homogenate, and ferment at room temperature for 60 hours;

[0028] 2) Supercritical extraction: import the fermented liquid into the extraction kettle, start the supercritical device, CO 2 The gas is filtered by the filter at a flow rate of 20L / h, and then pumped into the extraction tank by the compressor until the set pressure is 25MPa. The extraction temperature is controlled by the circulating water in the jacket of the extraction tank and stabilized at 40°C. At the same time, beeswax is introduced as an entrainer , at an extraction temperature of 40°C, a fluid pressure of 25MPa, and a flow rate of 0.4ml / min, extract for 2h to obtain an extract, CO 2 After the fluid extract reaches the separation tank to depressurize, it is separated from the extract, and the CO ...

Embodiment 3

[0033] 1) Microbial treatment: wash and slice ginseng, then add equal weight of distilled water and stir evenly, and homogenize under high pressure for 3 hours to obtain a homogenate, add Lactobacillus rhamnosus to the homogenate, and ferment at room temperature for 45 hours;

[0034] 2) Supercritical extraction: import the fermented liquid into the extraction kettle, start the supercritical device, CO 2 The gas is filtered by the filter at a flow rate of 20L / h, and then pumped into the extraction tank by the compressor until the set pressure is 20MPa. The extraction temperature is controlled by the circulating water in the jacket of the extraction tank and stabilized at 40°C. At the same time, beeswax is introduced as an entrainer , at an extraction temperature of 40°C, a fluid pressure of 20 MPa, and a flow rate of 0.2ml / min, extract for 3 hours to obtain an extract, CO 2 After the fluid extract reaches the separation tank to depressurize, it is separated from the extract, a...

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PUM

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Abstract

The invention relates to an extraction method of ginsenoside. By the extraction method, the conventional production technology is changed, the ginsenoside is extracted through biological fermentation,raw materials can be directly used without being dried, the energy consumption is low, the added value is high, and the extraction efficiency is high; with supercritical carbon dioxide as an extractant, the extraction method has the characteristics of environment friendliness, no toxicity, no residue and the like; and with beeswax as an entrainer, the extraction content of ginsenoside can be significantly increased.

Description

technical field [0001] The invention relates to an extraction process, in particular to a method for extracting ginsenosides. Background technique [0002] Ginseng (PanaxginsengC.A.Mey) is a perennial herb that likes shade. The leaves have no pores and palisade tissue, and cannot retain water. The leaves will burn when the temperature is higher than 32 degrees. The canopy density is 0.7‐0.8. It usually blooms in 3 years and bears fruit in 5-6 years. The flowering period is May-June and the fruiting period is June-September. It grows in coniferous and broad-leaved mixed forests or deciduous broad-leaved forests dominated by Korean pine at an altitude of several hundred meters between 33°-48° north latitude. It is produced in Northeast China, North Korea, South Korea, Japan, and eastern Russia. The other names of ginseng are yellow ginseng, goblin, and god grass. Ginseng root contains 0.4% ginsenoside and a small amount of volatile oil. The main ingredient in the oil is 0.0...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/258
CPCA61K36/258A61K2236/19A61K2236/37A61K2236/51A61K2236/55
Inventor 王飞利
Owner 佛山市飞程信息技术有限公司
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