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Sishun Qingliangyin granules and preparation process thereof

A granule, cooling technology, applied in antiviral agents, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc. To achieve good infusion and taste, easy granulation, easy to carry

Active Publication Date: 2021-06-29
GUANGZHOU JINAN BIOMEDICINE RES & DEV CENT
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the auxiliary material of this invention is granulated with soluble starch and dextrin at a ratio of 1:1, and the resulting granules have poor flushability, which affects mouthfeel and drug efficacy.

Method used

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  • Sishun Qingliangyin granules and preparation process thereof
  • Sishun Qingliangyin granules and preparation process thereof
  • Sishun Qingliangyin granules and preparation process thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1 4

[0055] Example 1 Sishun Qingliang Drink Granules

[0056] Weigh 3 kg each of rhubarb, red peony root, licorice and angelica, add pure water with a weight-to-volume ratio of medicinal materials of 9, reflux extraction 3 times, combine the extracts, let stand overnight, filter, and concentrate the filtrate under reduced pressure to obtain relative Density 1.25g / cm 3 9.7kg of medicinal extract; Get the gained medicinal extract and adjuvant with the mass ratio mixing of extractum: dextrin: bifidosaccharide: hyaluronic acid=3:3:1:2, stir evenly, granulate, dry 3h at 50 ℃, Whole grains, Desi Shun Qingliang Drink Granules.

Embodiment 2 4

[0057] Example 2 Sishun Qingliang Drink Granules

[0058] Weigh 3 kg each of rhubarb, red peony root, licorice and angelica, add pure water with a weight-to-volume ratio of medicinal materials of 9, reflux extraction 3 times, combine the extracts, let stand overnight, filter, and concentrate the filtrate under reduced pressure to obtain relative Density 1.23g / cm 3 9.8kg of medicinal extract; get the gained extract and adjuvant to mix with the mass ratio of extract: dextrin: bifidosaccharide: hyaluronic acid=3:3:1:2, stir evenly, granulate, dry at 55°C for 3h, Whole grains, Desi Shun Qingliang Drink Granules.

Embodiment 3 4

[0059] Example 3 Sishun Qingliang Drink Granules

[0060] Weigh 3 kg each of rhubarb, red peony root, licorice and angelica, add pure water with a weight-to-volume ratio of medicinal materials of 9, reflux extraction 3 times, combine the extracts, let stand overnight, filter, and concentrate the filtrate under reduced pressure to obtain relative Density 1.20g / cm 3 10.1kg of the medicinal extract; get the obtained extract and auxiliary materials to mix with the mass ratio of extract: dextrin: bifidosaccharide: hyaluronic acid = 3:3:1:2, stir evenly, granulate, dry at 55°C for 3h, Whole grains, Desi Shun Qingliang Drink Granules.

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Abstract

The invention belongs to the field of traditional Chinese medicine preparations, and in particular relates to a Sishun Qingliangyin granule and a preparation process thereof. The Sishun Qingliangyin granule comprises the following raw materials and parts by weight: 45-55 parts of rhubarb, 45-55 parts of red peony, 45-55 parts of licorice and 45-55 parts of angelica; it also includes dextrin, bifidosaccharide and hyaluronic acid as excipients. The Sishun Qingliangyin granule prepared by the invention is convenient to use, has good drug efficacy, solubility and mouthfeel, and also has antiviral and antibacterial effects.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine preparations, and in particular relates to a Sishun Qingliangyin granule and a preparation process thereof. Background technique [0002] Sishun Qingliang Decoction is a traditional Chinese medicine compound (4 ingredients), its composition is simple and reasonable. The "Dictionary of Traditional Chinese Medicine" records that the function of Sishun Qingliang Decoction is to treat children's blood congestion, heat accumulation in the lungs and viscera, red cheeks and thirst. Five heart troubles and fever, restless sleeping, trembling of limbs, gastrointestinal disorders, astringent defecation, or wind-heat tuberculosis, sores on the head and face, red eyes and sore throat, herpes residual poison, and diarrhea. There are also records in "Miscellaneous Syndrome Bianmeng", "Medical Mind Enlightenment" and "Examining Yao Letters". However, the original prescription of Sishun Qingliang Drin...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/16A61K36/71A61K36/708A61K47/36A61K47/26A61P31/14A61P31/20A61P31/04
CPCA61K9/1623A61K9/1652A61K36/232A61K36/484A61K36/65A61K36/708A61K36/71A61K2236/331A61K2236/39A61P31/04A61P31/14A61P31/20A61K2300/00
Inventor 王一飞廖晓凤王治平
Owner GUANGZHOU JINAN BIOMEDICINE RES & DEV CENT