Liposome structure for achieving skin cleaning and anti-aging, composition and preparation method

A technology for skin cleansing and liposomes, applied in skin care preparations, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve problems in the initial stage and have not formed a perfect market, so as to increase stability and eliminate Wrinkles, improve the effect of scavenging free radicals

Active Publication Date: 2018-09-07
润芳可(上海)生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, cosmetics containing various liposomes are relatively common in developed countries, bu

Method used

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  • Liposome structure for achieving skin cleaning and anti-aging, composition and preparation method
  • Liposome structure for achieving skin cleaning and anti-aging, composition and preparation method
  • Liposome structure for achieving skin cleaning and anti-aging, composition and preparation method

Examples

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[0027] Example 1

[0028] Weigh 15 parts of lecithin and 85 parts of soybean phospholipids by weight in a mixture of chloroform and methanol (v:v=1:1), add 30 parts of jojoba oil, 25 parts of vitamin E, 20 parts Parts of superoxide dismutase and 10 parts of dipalmitoyl hydroxyproline were evaporated under reduced pressure to remove the organic solvent to form a thin film. Add a phosphate buffer solution with a pH of 6.5 and a concentration of 8mmol / L, mechanically stir and hydrate for 3h at a temperature of 50°C to obtain a suspension and stand for 24h, and centrifuge to obtain liposome A. Weigh 45 parts of sphingomyelin, 15 parts of cholesterol, 15 parts of fatty acids, 15 parts of phosphatidylcholine and 10 parts of cholesterol sulfate in a mixture of chloroform and methanol (v:v=1:1) Add 10 parts of glutathione, 25 parts of fruit acid, 35 parts of vitamin C, 10 parts of retinol, 5 parts of coenzyme Q10, and evaporate the organic solvent under reduced pressure to form a thin f...

Example Embodiment

[0029] Example 2

[0030] Weigh 15 parts of lecithin and 85 parts of soybean phospholipids by weight in a mixture of chloroform and methanol (v:v=1:1), add 40 parts of jojoba oil, 30 parts of vitamin E, 30 parts Parts of superoxide dismutase and 20 parts of dipalmitoyl hydroxyproline were evaporated under reduced pressure to remove the organic solvent to form a thin film. A phosphate buffer solution with a pH of 6.5 and a concentration of 8 mmol / L was added, and the suspension was mechanically stirred and hydrated for 3 hours at a temperature of 45° C. to obtain a suspension and allowed to stand for 24 hours. After centrifugation, liposome A was obtained. Weigh 45 parts of sphingomyelin, 15 parts of cholesterol, 15 parts of fatty acids, 15 parts of phosphatidylcholine and 10 parts of cholesterol sulfate dissolved in chloroform and methanol (v:v=1:1) In the mixed solution, 15 parts of glutathione, 30 parts of fruit acid, 45 parts of vitamin C, 10 parts of retinol, and 10 parts of...

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Abstract

The invention relates to the technical field of cosmetics, in particular to a liposome structure for achieving skin cleaning and anti-aging, a composition and a preparation method. The composition iscomposed of liposome A and liposome B which are of different structures according to the weight ratio of 1:1; the liposome A is of a multi-layer liposome structure and is formed in the mode that a wall material wraps a skin cleaning composition, and the component of the wall material of the liposome A is lecithin and soybean phospholipid; the liposome B is of a single-layer liposome structure andis formed in the mode that a wall material wraps a skin anti-aging composition, and the component of the wall material of the liposome B is sphingomyelin, cholesterol, fatty acid, phosphatidylcholineand cholesterol sulfate. According to the liposome structure, the liposome A and liposome B which are different in particle diameter, size and structure are adopted for wrapping the skin cleaning composition and the skin anti-aging composition respectively and applied to the skin surface and the skin deep layer respectively, and through mutual cooperation and promotion of various active substances, the obvious effects of skin cleaning and anti-aging can be achieved.

Description

technical field [0001] The invention relates to the technical field of cosmetics, more specifically, to a liposome structure, composition and preparation method for realizing skin cleansing and anti-aging. Background technique [0002] In recent years, the cosmetics market has developed very rapidly. Cosmetics refer to products that are spread on the surface of the human body such as the skin by smearing, spraying or other similar methods to achieve the purpose of cleaning, maintenance, beauty and anti-aging, including facial cleanser, essence, mask, etc. With the improvement of people's living standards, consumers have higher and higher requirements for the efficacy of cosmetics. This makes active ingredients with high efficacy to be continuously discovered and applied in the development of cosmetic formulations. In this process, there are two problems that limit the effective application of many active ingredients with special efficacy. First, many active ingredients, s...

Claims

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Application Information

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IPC IPC(8): A61K8/14A61K8/02A61K8/92A61K8/36A61K8/365A61K8/44A61K8/55A61K8/63A61K8/64A61K8/66A61K8/67A61K8/68A61K8/35A61Q19/08A61Q19/10
CPCA61K8/025A61K8/14A61K8/355A61K8/361A61K8/365A61K8/44A61K8/553A61K8/63A61K8/64A61K8/66A61K8/671A61K8/676A61K8/678A61K8/68A61K8/922A61K2800/592A61Q19/08A61Q19/10
Inventor 高文红王伟蒋琰郑芸王一辰刘明富
Owner 润芳可(上海)生物科技有限公司
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