Preparation and use method of royal paulowinia flower polysaccharide traditional Chinese medicine immunoenhancer

The technology of an immune enhancer and paulownia flower, which is applied in the direction of medical formula, medical preparations containing active ingredients, drug combinations, etc., can solve the problems of inconvenient, large dosage of traditional Chinese medicine, and difficult mixing, so as to reduce the preparation cost, immune The effect of reducing the total amount of enhancer and improving the production rate

Active Publication Date: 2018-09-25
JIANGSU AGRI ANIMAL HUSBANDRY VOCATIONAL COLLEGE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition to this patent, a number of technical solutions of traditional Chinese medicine immune enhancers have also been disclosed. However, during the use of these technical immune enhancers, they are all added to poultry feed throughout the process, which requires daily feeding before feeding. It is necessary to add traditional Chinese medicine enhancer to the

Method used

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  • Preparation and use method of royal paulowinia flower polysaccharide traditional Chinese medicine immunoenhancer
  • Preparation and use method of royal paulowinia flower polysaccharide traditional Chinese medicine immunoenhancer
  • Preparation and use method of royal paulowinia flower polysaccharide traditional Chinese medicine immunoenhancer

Examples

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Comparison scheme
Effect test

Embodiment 1

[0025] A method for preparing and using a paulownia flower polysaccharide traditional Chinese medicine immune enhancer, which comprises the following steps:

[0026] (1) Take 500g of paulownia flower herbs, add water to moisten and wash to remove mud;

[0027] (2) Add 5kg of water for the first decoction, and filter the decoction after decoction; add 5kg of water for the second decoction, and filter the decoction after decoction; Then the 2 filtrates were combined and concentrated to obtain a 500mL concentrate;

[0028] (3) Centrifuge the concentrated solution and take the supernatant;

[0029] (4) Add ethanol that is 4 times the weight of the centrifuged liquid into the centrifuged liquid, and stir it, and let it stand for more than 12 hours after stirring; the ethanol concentration is 95%;

[0030] (5) After taking out the upper liquid of the static liquid and discarding it, then take out the lower liquid of the static liquid to obtain a paste;

[0031] (6) Dry the paste ...

Embodiment 2

[0036] A method for preparing and using a paulownia flower polysaccharide traditional Chinese medicine immune enhancer, which comprises the following steps:

[0037] (1) Take 500g of paulownia flower herbs, add water to moisten and wash to remove mud;

[0038] (2) Add 5kg of water for the first decoction, and filter the decoction after decoction; add 5kg of water for the second decoction, and filter the decoction after decoction; Then the 2 filtrates were combined and concentrated to obtain a 500mL concentrate;

[0039] (3) Centrifuge the concentrated solution and take the supernatant;

[0040] (4) Add ethanol that is 4 times the weight of the centrifuged liquid into the centrifuged liquid, and stir it, and let it stand for more than 12 hours after stirring; the ethanol concentration is 95%;

[0041] (5) After taking out the upper liquid of the static liquid and discarding it, then take out the lower liquid of the static liquid to obtain a paste;

[0042] (6) Dry the paste ...

Embodiment 3

[0047] A method for preparing and using a paulownia flower polysaccharide traditional Chinese medicine immune enhancer, which comprises the following steps:

[0048] (1) Take 500g of paulownia flower herbs, add water to moisten and wash to remove mud;

[0049] (2) Add 5kg of water for the first decoction, and filter the decoction after decoction; add 5kg of water for the second decoction, and filter the decoction after decoction; Then the 2 filtrates were combined and concentrated to obtain a 500mL concentrate;

[0050] (3) Centrifuge the concentrated solution and take the supernatant;

[0051] (4) Add ethanol that is 4 times the weight of the centrifuged liquid into the centrifuged liquid, and stir it, and let it stand for more than 12 hours after stirring; the ethanol concentration is 95%;

[0052] (5) After taking out the upper liquid of the static liquid and discarding it, then take out the lower liquid of the static liquid to obtain a paste;

[0053] (6) Dry the paste ...

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Abstract

The invention provides a preparation and use method of a royal paulowinia flower polysaccharide traditional Chinese medicine immunoenhancer. Polysaccharide is extracted from royal paulowinia flower medicine materials to prepare the traditional Chinese medicine immunoenhancer. A 18-day-old non-immunized chicken is taken, a nose and eyes of the chicken are dropped by a newcastle disease vaccine IV,so that the chicken is firstly immunized, the chicken is secondly immunized when growing for 32 days, the chicken is drenched once every one day with royal paulowinia flower polysaccharide solution through a mouth when the chicken is immunized every time, the administration dosage is 12.5-50mg/kg, and the chicken is continuously drenched with the royal paulowinia flower polysaccharide solution forthree days, measurement is performed on the seventh day, fourteenth day, twenty-first day and twenty-eighth day after the chicken is firstly immunized, results discover that royal paulowinia flower polysaccharide can obviously facilitate appreciation of peripheral blood and splenic lymphocytes of the chicken, ND-HI antibody level is improved, immune organ indexes are improved, the concentration of cell factors such as IL-4, IL-6 and IFN-g in serum is improved, the content of duodenum SIgA is improved, so that immunity of a body is improved, and the immune effect of a vaccine is enhanced.

Description

technical field [0001] The invention belongs to the field of immune enhancers, in particular to a traditional Chinese medicine immune enhancer used for poultry and livestock. Background technique [0002] In recent years, my country's animal husbandry has developed rapidly, and the risks caused by major animal diseases to the animal husbandry have become increasingly prominent, especially in recent years, avian influenza, Newcastle disease, porcine reproductive and respiratory syndrome, porcine circovirus disease, swine fever The epidemic of livestock and poultry infectious diseases, the animal husbandry has suffered a huge impact, and even endangered public health security, which has seriously affected the current and future healthy development of my country's animal husbandry. Most of these harmful diseases are viral infectious diseases, and some are immunosuppressive diseases. So far, people have not found a specific treatment drug. In addition to strengthening feeding m...

Claims

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Application Information

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IPC IPC(8): C08B37/00A61K31/715A61P37/02
CPCA61K31/715C08B37/0003
Inventor 杨海峰蒋春茂陈晓兰张萍邱树磊张建李艳艳贾纪萍黄陈沈小洁
Owner JIANGSU AGRI ANIMAL HUSBANDRY VOCATIONAL COLLEGE
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