Polypeptide reactor

Abstract

The invention discloses a polypeptide reactor. The polypeptide reactor comprises a kettle body, wherein a feeding opening is formed in the upper end of the kettle body; a discharging opening is formedin the lower end of the kettle body; a stirring unit is arranged in the kettle body and comprises a plurality of stirring devices; each stirring device comprises a rotating sleeve shaft; each rotating sleeve shaft comprises a rotating shaft and a driving shaft inserted in the rotating shaft; the center line of the rotating shaft is perpendicular to the center line of the kettle body; the center lines of the various rotating shafts are parallel to one another; a plurality of stirring blades are uniformly arranged on the periphery of each rotating shaft; a plurality of mesh holes are formed ineach stirring blade; and the lower end of the kettle body is externally connected with a vacuumizing unit. By the design, the structure is simple and clear, the various assemblies are connected closely and do not interfere one another, required components are changed conveniently, maintenance of the product in a using process in the future is facilitated, and the invention aims to solve the problems that in the prior art, a liquid-phase polypeptide synthesis reactor is low in reaction efficiency and low in product purification degree.

Description

technical field [0001] The invention relates to chemical equipment, in particular to a polypeptide reactor. Background technique [0002] In the 1990s, the research in the field of peptides entered a new stage of development. Studies have shown that active peptides with a very small amount in organisms play an important role in regulating the life process. These active peptides are closely related to biological development, growth metabolism, immunity, disease, school, memory and aging, so scientists from various countries, including organic scientists, biologists, pharmacologists, structural chemists, etc., are closely related to life Science-related scientists are highly regarded. [0003] Polypeptide synthesis is a process of repeated addition of amino acids. The solid-phase synthesis sequence is generally synthesized from the C-terminus (carboxyl-terminus) to the N-terminus (amino-terminus). Liquid-phase peptide synthesis is still widely used, and it is useful in the sy...

AI Technical Summary

Problems solved by technology

[0004] In order to solve the above problems, the present invention discloses a polypeptide reactor, the purpose of which is to solve the problems of low reaction efficiency and low product purity in liquid phase polypeptide synthesis reactors in the prior art

The design structure is simple and clear, the components are closely connected without interfering with each other, the required parts are easy to replace, and it is easy to maintain the product during use in the future. By designing the stirring unit in the reactor body, the current low reaction efficiency is overcome. The problem is that the centerline of the rotating shaft in the stirring unit and the centerline of the kettle body are perpendicular to each other, the centerlines of each of the rotating shafts are parallel to each other, and a number of stirring blades are evenly arranged on the outer circumference of the rotating shaft, and the stirring blades There are several mesh holes on the top, which can ensure that the stirring shaft is stably fixed in the kettle body during the stirring process, avoiding the problem of device instability during the reaction process; by designing mesh holes on the stirring blades, it is possible to realize the reaction during the stirring process The materials are fully mixed and stirred, and with the vacuum unit, during the reaction process, the air in the reactor body is evacuated to create a convenient environment for the reaction. Multiple stirring devices are installed to prevent the material at the lower end of the reactor body from depositing at the lower end. On the other hand, It can prevent the material from reacting with other impurities and affect the quality of the finished product

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