Quick and nondestructive chdecalciferolchdes terol content quantitative method based on Raman full spectrum analysis

A full-spectrum analysis and cholerevidin technology, which is applied in the field of non-destructive and fast choleretin content quantification, can solve the problems of unsuitable choleretin content quantitative analysis, achieve choleretin content, solve spectral peak shift and intensity The effect of the influence of error

Inactive Publication Date: 2018-11-13
SHANGHAI JIAO TONG UNIV
View PDF5 Cites 10 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0014] Existing studies have used Raman spectroscopy to quantitatively analyze the composition and content of substances, and often use one or several characteristic peaks of Raman spectra of substances as training d

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Quick and nondestructive chdecalciferolchdes terol content quantitative method based on Raman full spectrum analysis
  • Quick and nondestructive chdecalciferolchdes terol content quantitative method based on Raman full spectrum analysis
  • Quick and nondestructive chdecalciferolchdes terol content quantitative method based on Raman full spectrum analysis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0047] The present invention will be described in detail below in conjunction with specific embodiments. The following examples will help those skilled in the art to further understand the present invention, but do not limit the present invention in any form. It should be noted that those skilled in the art can make several modifications and improvements without departing from the concept of the present invention. These all belong to the protection scope of the present invention.

[0048] The invention provides a non-destructive and fast quantification method for choleretin content based on Raman spectrum full-spectrum analysis, and can quickly and non-destructively detect spectral signals of different choleretin contents by suggesting a predictive analysis model. For specific implementation, you can refer to the following steps:

[0049] Step 1, cholesterol and vitamin mixture and cholerevidin are formulated into samples of different mass percentage content cholevetin;

[...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a quick and nondestructive chdecalciferolchdes terol content quantitative method based on Raman full spectrum analysis. The method comprises the following steps: step 1, preparing chdecalciferolchdes terol samples with contents in different mass percents by cholesterol, a vitamin mixture and chdecalciferolchdes terol; step 2, measuring spectral signals of the samples with different chdecalciferolchdes terol contents through a Raman spectrometer, so as to obtain Raman spectrometer data after pretreatment; step 3, carrying out analysis and treatment on pretreated Raman spectrometer full spectrum data by adopting a multivariate statistics analysis method so as to build a quantitative analysis model; step 4, carrying out quantitative analysis on chdecalciferolchdes terol in a tested sample with unknown chdecalciferolchdes terol content by using the built quantitative analysis model. The method provided by the invention effectively prevents quantitative measurement accuracy from being influenced by Raman spectrum peak deviation of the chdecalciferolchdes terol samples; according to the method provided by the invention, through prediction and analysis of the model, prediction to chdecalciferolchdes terol samples with different contents can be achieved, and results prove the effectiveness of the full spectrum analysis based on Raman spectrum in chdecalciferolchdes terol content quantitative analysis.

Description

technical field [0001] The invention relates to a method for quantifying the content of choleretin, in particular to a non-destructive and rapid method for quantifying the content of choleretin based on Raman full-spectrum analysis. Background technique [0002] Cholevidin is a safe and effective clinical commonly used drug for the prevention and treatment of rickets. It can promote the absorption and utilization of calcium and phosphorus and promote normal bone calcification. Its curative effect is equivalent to that of intramuscular injection of vitamin D. In order to ensure the curative effect, it is necessary to detect the content of cholerevidin in the production process of the drug and the quality control of the finished product. It is of great significance to study the method of non-destructive and rapid quantification of the content of cholerectin. [0003] The raw material of cholerevidin is crystal, and only a few literatures have reported that it is composed of vi...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): G01N21/65
Inventor 黄梅珍徐荟迪林露璐徐永浩
Owner SHANGHAI JIAO TONG UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap