Animal oral immunization vaccine vector and preparation method thereof

An immunization vaccine and vaccine carrier technology, applied in the field of animal oral immunization vaccine carrier and its preparation, can solve the problems of incomplete disinfection, inability to determine complete disinfection, and high labor intensity, so as to reduce operating costs and protection costs, and reduce human infection. risks and improve economic efficiency

Inactive Publication Date: 2018-11-20
灵格技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] It can be seen that in the process of implementing operational immunization in the prior art, there are mainly the following problems: the cooperation of three staff members is required, the labor remuneration of the three people, the protection cost of the three people, the high cost of immunization, the high labor intensity, and the During the operation, due to the resistance of the animals, the accurate dose of the vaccine cannot be fed, which will cause the vaccine to leak, disperse the poison to the environment, and there is a risk of human infection
[0004] After the immunization is over, the disposable protective clothing needs to be harmlessly treated, and the method of incineration or deep burial is easy to cause pollution to the environment
When cleaning the dosing device, a large amount of water and disinfectants need to be used, causing pollution to the environment
After the doser is cleaned, it is impossible to determine whether the disinfection is complete, and there are certain potential safety hazards
At present, there have been cases in China where children have been infected by contact with incompletely sterilized drug dispensers

Method used

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  • Animal oral immunization vaccine vector and preparation method thereof
  • Animal oral immunization vaccine vector and preparation method thereof
  • Animal oral immunization vaccine vector and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Embodiments of the present invention provide a method for preparing an animal oral immunization vaccine carrier, the method comprising:

[0033] The first step is to select qualified water spinach that meets the requirements of the plan, wash it, dry it and send it to the laboratory.

[0034] In the second step, the vaccine is diluted in the laboratory with a dose of one vaccine per 0.5ml of vaccine liquid.

[0035] The third step is to select two cavities on the spinach stem that can hold 1ml of liquid respectively, see figure 1 ; Draw the diluted vaccine solution with a syringe, and insert the needle obliquely into one of the cavities, see figure 2 , and inject the vaccine solution into the other cavity through the node in the middle of the two cavities, figure 1 and figure 2 The location of the node and the direction of the specific injection of the vaccine solution are marked by marking.

[0036] The fourth step, after the injection of the vaccine liquid, se...

Embodiment 2

[0042] The embodiment of the present invention also provides a preparation method of an animal oral immunization vaccine carrier, the method comprising:

[0043] The first step is to select qualified water spinach that meets the requirements of the plan, wash it, dry it and send it to the laboratory.

[0044] In the second step, the vaccine is diluted in the laboratory with a dose of one vaccine per 0.5ml of vaccine liquid.

[0045]The third step is to select two cavities on the spinach stem that can hold 1ml of liquid respectively, draw out the diluted vaccine solution with a syringe, insert the needle obliquely into one of the cavities, and pass through the node in the middle of the two cavities to dispense the vaccine solution. Inject into another cavity.

[0046] The fourth step, after the injection of the vaccine liquid, seal the eye of the needle with red edible glue, so as to prevent the vaccine liquid from flowing out and facilitate the inspection of the position of t...

Embodiment 3

[0052] The embodiment of the present invention also provides a preparation method of an animal oral immunization vaccine carrier, the method comprising:

[0053] The first step is to select qualified water spinach that meets the requirements of the plan, wash it, dry it and send it to the laboratory.

[0054] In the second step, the vaccine is diluted in the laboratory with a dose of one vaccine per 0.5ml of vaccine liquid.

[0055] The third step is to select two cavities on the spinach stem that can hold 1ml of liquid respectively, draw out the diluted vaccine solution with a syringe, insert the needle obliquely into one of the cavities, and pass through the node in the middle of the two cavities to dispense the vaccine solution. Inject into another cavity.

[0056] The fourth step, after the injection of the vaccine liquid, seal the eye of the needle with red edible glue, so as to prevent the vaccine liquid from flowing out and facilitate the inspection of the position of ...

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PUM

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Abstract

The invention discloses a method for preparing an animal oral immunization vaccine vector. The preparation method comprises the following steps: taking green vegetables as a vaccine vector, and injecting vaccine liquid in a first vaccine dose on the vaccine vector; sterilizing the vaccine vector, naturally airing, refrigerating and preserving, thereby obtaining the product. The animal oral immunization vaccine vector prepared according to the preparation method disclosed in the invention is prepared by enabling the green vegetables that are often fed to animals to carry the immunized vaccine liquid. Therefore, when the green vegetables are broken by teeth of the animals, the stem chambers containing the vaccine liquid are broken in animal mouths, the vaccine liquid flows out, the vaccine liquid is in sufficient contact with the animal mouths by virtue of repeated chewing of the animals, and the expected mucosal immunity is achieved. After the residues of the green vegetables are directly eaten, poisoning to the outside is avoided, and nutrition needed by the animals is supplemented.

Description

technical field [0001] The application relates to the field of breeding, in particular to an animal oral immunization vaccine carrier and a preparation method thereof. Background technique [0002] At present, there are mainly two ways of immunizing animals, such as cattle or sheep, with vaccines, one is injection immunization and the other is oral immunization. Oral immunization is divided into two types: gavage and drinking water. Because drinking water is easy to cause poison, it is not used at present. When instilling vaccines against severe zoonotic infectious diseases, three staff members are required to wear protective clothing to cooperate. One is responsible for fixing the livestock, one is responsible for administering the medicine, and one is responsible for assisting the other two. During the immunization process, because the individual animals are large and not easy to fix, the resistance of the animals during administration will cause personal injury and vacci...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K47/46A61K39/00A61P37/04A61L2/18A61L101/34
CPCA61K39/00A61K47/46A61K2039/542A61L2/18A61P37/04
Inventor 霍婧媛王泽仁崔春生陈礼朋刘礼杰蔡瑞东于树军
Owner 灵格技术有限公司
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