Coating technology of pancreatic kininogenase enteric-coated tablets
A pancreatic kininogenase, enteric-coated tablet technology, applied in the directions of peptidase, enzyme, hydrolase, etc., can solve the problems of appearance, dissolution, reduced stability, instability, easily affecting product quality, etc. Complete, stable, high dissolution effect
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[0020] Example 1: A coating process of pancreatic kininogenase enteric-coated tablets, including the following steps:
[0021] Step 1. Prepare materials according to the mass parts of the following components: 100 parts of plain tablets, 1.5 parts of gastric-soluble film-coating pre-mixed auxiliary materials, and 5 parts of enteric film-coated pre-mixed auxiliary materials;
[0022] Step 2. Add the gastric-soluble film coating pre-mixed auxiliary material of the formula in Step 1 into 80% ethanol (80% ethanol is made of 95% ethanol and purified water) and stir evenly in a slurry pot or stainless steel bucket to make A solution of gastric-soluble film-coating pre-mixed excipients with a concentration of 10%; add the enteric-coated film-coating pre-mixed excipients in step 1 to 80% ethanol (80% ethanol is made of 95% ethanol and purified water) Stir evenly in a pulping pot or stainless steel barrel to prepare a 10% enteric-coated film coating premixed auxiliary material solution;
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Example Embodiment
[0030] Example 2: A coating process of pancreatic kininogenase enteric-coated tablets, including the following steps:
[0031] Step 1. Prepare materials according to the mass parts of the following components: 100 parts of plain tablets, 2 parts of gastric-soluble film-coating pre-mixed auxiliary materials, and 5.5 parts of enteric-coated film-coated pre-mixed auxiliary materials;
[0032] Step 2. Add the gastric-soluble film coating pre-mixed auxiliary material of the formula in Step 1 into 80% ethanol (80% ethanol is made of 95% ethanol and purified water) and stir evenly in a slurry pot or stainless steel bucket to make A solution of gastric-soluble film-coating pre-mixed excipients with a concentration of 10%; add the enteric-coated film-coating pre-mixed excipients in step 1 to 80% ethanol (80% ethanol is made of 95% ethanol and purified water) Stir evenly in a pulping pot or stainless steel barrel to prepare a 10% enteric-coated film coating premixed auxiliary material soluti...
Example Embodiment
[0040] Example 3: A coating process of pancreatic kininogenase enteric-coated tablets, including the following steps:
[0041] Step 1. Prepare materials according to the mass parts of the following components: 100 parts of plain tablets, 2.5 parts of gastric-soluble film-coating pre-mixed adjuvants, and 6 parts of enteric film-coated pre-mixed adjuvants;
[0042] Step 2. Add the gastric-soluble film coating pre-mixed auxiliary material of the formula in Step 1 into 80% ethanol (80% ethanol is made of 95% ethanol and purified water) and stir evenly in a slurry pot or stainless steel bucket to make A solution of gastric-soluble film-coating pre-mixed excipients with a concentration of 10%; add the enteric-coated film-coating pre-mixed excipients in step 1 to 80% ethanol (80% ethanol is made of 95% ethanol and purified water) Stir evenly in a pulping pot or stainless steel barrel to prepare a 10% enteric-coated film coating premixed auxiliary material solution;
[0043] Step 3. Start t...
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