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Computer-aided model construction method based on deep learning gastric cancer pathological sections

A computer-aided pathological slicing technology, applied in computer parts, calculation, and recognition of medical/anatomical patterns, etc., can solve difficult morphological features, texture features and related structural descriptions, and it is difficult to extract distinguishable high-quality Features, general recognition accuracy and other issues, to achieve the effect of avoiding overfitting, high sensitivity, and high recognition accuracy

Active Publication Date: 2018-11-27
BEIJING UNIV OF TECH
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AI Technical Summary

Problems solved by technology

First of all, when performing pathological image segmentation and feature extraction, researchers are required to have professional knowledge in related fields, otherwise it is difficult to describe the morphological features, texture features and related structures in the sample slices
At the same time, pathological images are often very complex, and traditional methods may be difficult to extract distinguishing high-quality features, resulting in relatively general recognition accuracy

Method used

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  • Computer-aided model construction method based on deep learning gastric cancer pathological sections
  • Computer-aided model construction method based on deep learning gastric cancer pathological sections
  • Computer-aided model construction method based on deep learning gastric cancer pathological sections

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Embodiment Construction

[0045] The present invention will be described in further detail below in conjunction with specific embodiments and with reference to the accompanying drawings.

[0046] The hardware used in the present invention is a workstation capable of deep learning. The auxiliary tool used is the deep learning training framework Keras.

[0047] The computer-aided diagnosis model construction method of gastric cancer pathological slices based on deep learning provided by the present invention mainly includes the following steps:

[0048] Step 1, build a 121-layer DenseNet model, such as Figure 8 As shown in , the backbone of the model is composed of 4 gradually deepening dense structures and 4 transition layers alternately spliced. Among them, the transition layer structure and the basic convolutional structure distribution of the dense structure are as follows: figure 2 and figure 1 . In each dense structure, before each convolution operation starts, the results of each previous c...

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Abstract

The invention discloses a computer aided model construction method based on deep learning gastric cancer pathological sections, and belongs to the technical field of artificial intelligence. The method uses a 121-layer dense-connected convolutional neural network to perform image recognition. A dense block structure in a DenseNet allows the high-level part of the network to acquire shallow features, which greatly reduces the over-fitting phenomenon. At the same time, the model has a large number of layers, which can fit more complex and smoother decision functions. Although the number of layers is large, the number of parameters of the model is not large, which saves resource consumption. In order to further avoid over-fitting, a training mechanism for migration learning is adopted. The model will be pre-trained on an ImageNet dataset to give the model a strong image feature extraction capability. The main optimization of the model during formal training can be better focused on how toextract the features of the diseased area, and the utilization rate of the data is greatly improved.

Description

technical field [0001] The invention belongs to the technical field of artificial intelligence, and mainly relates to a method for constructing a computer-aided recognition model of gastric cancer pathological slices based on a deep learning algorithm and using an attention mechanism to enhance the effect. Background technique [0002] Gastric cancer is the fourth most common cancer in the world, and its death rate is the second highest among all cancers. Therefore, gastric cancer has gradually become a public health problem of general concern. And if patients can be diagnosed in the early stage of gastric cancer tumors, then the treatment of gastric cancer patients will achieve significant results and greatly reduce the mortality of gastric cancer diseases. The images of gastric cancer pathological sections are the images obtained by obtaining gastric tissue through biopsy, staining the tissue sections with Hematoxylin & Eosin (H&E), and then taking pictures with a digital...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06K9/62
CPCG06V2201/03G06F18/214
Inventor 刘博赵业隆
Owner BEIJING UNIV OF TECH
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