An experimental device for real-time monitoring of the support force distribution of vascular stents in a flow field environment

A real-time monitoring and vascular stent technology, which is applied in the field of mechanical performance testing of medical devices, can solve the problems of many uncertain factors and low precision, and achieve the effect of controllable flow and temperature

Active Publication Date: 2020-12-11
SOUTHEAST UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The accuracy of the anti-parallel plate extrusion performance test and the anti-V-groove extrusion performance test is relatively high, but the stress mode of the stent is different from the actual action mode in the vascular environment, so it can only be an indirect reflection of the radial strength of the stent ; The radial extrusion performance test simulates the actual situation of the stent in the blood vessel. While obtaining the radial compression force of the blood vessel on the stent, it can also obtain the chronic outstretching force of the stent on the blood vessel at the same time; the radial anti-hydraulic test It can also better simulate the stress shape of the stent in the blood vessel, but the accuracy is low and there are many uncertain factors

Method used

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  • An experimental device for real-time monitoring of the support force distribution of vascular stents in a flow field environment
  • An experimental device for real-time monitoring of the support force distribution of vascular stents in a flow field environment
  • An experimental device for real-time monitoring of the support force distribution of vascular stents in a flow field environment

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] Such as figure 2 As shown in the device, the selected test piece is a braided WE43 magnesium alloy balloon-expandable vascular stent 7. The stent is preloaded on the balloon catheter and delivered to the polyurethane PU transparent elastic tube 8, and the balloon is filled with the inflation pressure pump. When the balloon reaches the nominal pressure, the stent squeezes the polyurethane PU transparent elastic tube 8 outward, and at the same time the stent expands, and the balloon at the distal end of the catheter is withdrawn after decompression and contraction. The corrosive medium used is a simulated plasma solution at a temperature of 37°C , the velocity of the flow field is controlled by the speed-adjustable peristaltic pump 1. In the corrosive medium fluid, the radial support force of the magnesium alloy balloon-expandable vascular stent 7 decreases continuously with its own degradation, and the radial support of each part of the stent can be recorded in real time...

Embodiment 2

[0041] The device used is the same as that in Example 1, and the sample selected is a laser-engraved nickel-titanium alloy self-expanding vascular stent 7. The stent is preloaded on the delivery catheter and placed on the expanded polytetrafluoroethylene ePTFE elastic tube 8 In it, it is connected to the simulated blood circulation device through a silicone hose 5, the corrosive medium used is a simulated plasma solution, the velocity of the flow field is controlled by an adjustable-speed peristaltic pump 1, and the temperature is adjusted to 37°C until the transition temperature of the alloy is reached, and the bracket gradually Deformation expands and produces support force on the elastic tube, real-time recording of radial support force changes in the process of stent expansion and retraction, and research on the influence of blood flow on the radial support force of vascular stents.

Embodiment 3

[0043] The device used is based on the implementation of Case 1 or 2. A local annular plaque is added between the vascular stent and the simulated blood vessel wall. The selected test piece is a drug-eluting AZ31 magnesium alloy balloon-expandable vascular stent formed by laser engraving. 7. The surface has been treated with micro-arc oxidation. The material and size of the annular plaque can be adjusted, which can simulate different degrees of blockage and plaque hardening of the lesion. The stent is preloaded on the balloon catheter and delivered to the polyester transparent elastic tube In 8, the balloon is filled to the nominal pressure by using the filling pressure pump, the stent squeezes the polyester transparent elastic tube 8 outward, and at the same time the stent expands, and the balloon at the distal end of the catheter is withdrawn after decompression and contraction, and the corrosive medium used is simulated Plasma solution, the temperature is 37°C, the speed of ...

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Abstract

The invention discloses an experimental device for monitoring support force distribution of a vascular stent in a flow field environment in real time. The device comprises a speed-adjustable peristaltic pump (1), a liquid storage tank (2), a water bath box (3), a stent support force real-time monitoring device (4), silica gel flexible pipes (5) and pipe connectors (6), wherein the stent support force real-time monitoring device (4) comprises a vascular stent (7), a polymer transparent elastic tube (8), a piezoresistive thin-film pressure sensor (9), a polymer transparent rigid tube (10), a fixing sleeve (11), a data collector (12), a computer (13) and a container (14). The experimental device is simple in structure, low in cost and convenient to operate, can measure the radial support force of vascular stents with different materials and structures, and provides a scientific theoretical basis for establishing and perfecting a detection and evaluation system for radial mechanical properties of vascular stents.

Description

technical field [0001] The invention relates to an experimental device for real-time monitoring of the distribution of support force of a vascular stent in a flow field environment, belonging to the field of mechanical performance testing of medical devices. Background technique [0002] The radial mechanical properties of vascular stents are mainly reflected in the resistance of vascular stents to external pressure and the strain capacity of vascular stents to external forces. This characteristic determines whether the vascular stent can be tightly attached to the vessel wall. If the supporting force is too small, the lumen of the vascular stent will become smaller under the reaction force of the blood vessel, which will easily cause vascular embolism, and at the same time, the vascular stent will be easily displaced under the action of blood flow; while the supporting force is too large, it will cause local vessel wall damage (such as perforation). , tearing, rupture, etc....

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01L9/06
CPCG01L9/06
Inventor 储成林张真玮韩林原白晶薛烽郭超
Owner SOUTHEAST UNIV
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