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Composition with anti-depression function, preparation technology of composition and application in e-liquid

A technology for electronic cigarette oil and preparation process, which is applied in the field of tobacco technology and spices to achieve the effects of avoiding side effects, good process repeatability, and improving richness and sweetness.

Inactive Publication Date: 2018-12-25
CHINA TOBACCO HEBEI INDUSTRIAL CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the main functions of adding traditional Chinese medicine ingredients to e-cigarette oil are to clear the lungs and moisten the throat, freshen the breath, and provide different flavor types. However, there are no reports on the application of extracts with anti-depressant effects on e-cigarette oil.

Method used

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  • Composition with anti-depression function, preparation technology of composition and application in e-liquid
  • Composition with anti-depression function, preparation technology of composition and application in e-liquid
  • Composition with anti-depression function, preparation technology of composition and application in e-liquid

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] a. Mix accurately weighed 25g of Shichangpu, 40g of Morinda officinalis, 30g of tangerine peel, 25g of poria cocos, and 40g of radish seed, mix them and crush them to 200µm, then add water 10 times the total weight of the above-mentioned components, and extract by reflux method 2 times, each extraction for 2 hours, the obtained extract was concentrated under reduced pressure at 0.01Mp to the same weight of the total weight of each raw material, i.e. 210g, to obtain a water extract;

[0026] b. Add 10 times the amount of water after crushing 25 g of Amomum chinensis, extract 0.5 ml of volatile oil after extracting twice by steam distillation, then add 0.5 ml of volatile oil to the same volume of propylene glycol to obtain oil extract; The extraction time is 2 hours respectively, and the amount of water added each time is 3 times and 2 times of the weight of Amomum japonicus respectively;

[0027] c. After mashing 25g of bergamot, add 10 times the amount of 95% ethanol aq...

Embodiment 2

[0031] a. Mix accurately weighed 28 g of Shichangpu, 70 g of Morinda officinalis, 42 g of tangerine peel, 28 g of poria cocos, and 42 g of radish seed, mix them and grind them to 200 μm, then add water that is 8 times the total weight of the above-mentioned components, and use decoction Extracted twice, each extraction 2 hours, the extract obtained was concentrated under reduced pressure at 0.01Mp to the same weight of the total weight of each raw material, i.e. 210g, to obtain a water extract;

[0032] b. Add 10 times the amount of water after crushing 42g of Amomum chinensis, extract 0.5ml of volatile oil after extracting twice by steam distillation, then add 0.5ml of volatile oil to the same volume of propylene glycol to obtain oil extract; each time The extraction time is 2 hours and 3 hours respectively, and the amount of water added each time is 3 times and 4 times the weight of Amomum chinensis;

[0033] c. After mashing 49g of bergamot, add 8 times the amount of 95% et...

Embodiment 3

[0037] a. Mix accurately weighed 36g of Acorus shichangpu, 72g of Morinda officinalis, 24g of tangerine peel, 36g of poria cocos, and 42g of radish seed, mix them and grind them to 200µm, then add water 10 times the total weight of the above-mentioned components, and extract by reflux method 2 times, each extraction for 1.5 hours, the obtained extract was concentrated under reduced pressure at 0.01Mp to the same weight of the total weight of each raw material, namely 210g, to obtain a water extract;

[0038] b. Add 10 times the amount of water after pulverizing 48g of Amomum chinensis, and collect 0.5ml of volatile oil after 2 times of cold immersion extraction by supercritical extraction method, then add 0.5ml of volatile oil to the same volume of propylene glycol to obtain an oil extract, Each cold soaking extraction time is 1 hour and 3 hours respectively, and the amount of water added each time is 2 times and 4 times of the weight of Amomum chinensis;

[0039] c. After mas...

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Abstract

The invention discloses a composition with an anti-depression function. The composition is prepared from, by weight, 2-8 of acorus tatarinowii, 4-10 of fructus amomi, 6-15 of morinda officinalis, 3-8of bergamot, 2-6 of dried tangerine, 2-7 of poria cocos and 3-9 of semen raphani. A prepared water extract, a prepared oil extract and a prepared alcohol extract are uniformly mixed to obtain the composition with the anti-depression function. The composition is mixed with an e-liquid base and organic solvent to prepare the e-liquid. The raw materials of the composition are easy to obtain, and thepharmacological action is clear. The side effects of western medicine can be avoided, the fragrance is sweet, the rich degree and sweet performance of smoke are improved, a rat experiment shows that asignificant anti-depression effect is achieved, and the pharmacological activity of the composition is equal to even exceeds that of the anti-depression medicine venlafaxine. The effects of anti-depression, emotion easing and pleasuring are achieved, and the e-liquid quality is greatly improved. The preparation technology is good in repeatability and stable, has simple requirements for technologyequipment, and is suitable for large-scale industrial production.

Description

technical field [0001] The invention belongs to the field of tobacco technical spices, and in particular relates to a composition with antidepressant effect, a preparation method and its application in electronic cigarette oil, and electronic cigarette oil containing the composition. Background technique [0002] Depression, also known as depressive disorder, is the main type of mood disorder with significant and persistent low mood as the main clinical feature. It can be seen clinically that the mood is not commensurate with the situation. The depression of mood can range from gloomy to distraught, low self-esteem and depression, even pessimistic world-weariness, and there may be suicide attempts or behaviors; even stupor; some cases have obvious anxiety and motor agitation; In severe cases, psychotic symptoms such as hallucinations and delusions may appear. [0003] So far, the etiology of depression is not clear, but it is certain that many factors of biology, psychology...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A24B15/30A24F47/00A61K36/888A61K36/9064A61K36/746A61K36/752A61K36/076A61K36/31A61P25/24
CPCA24F47/002A24B15/30A61K36/076A61K36/31A61K36/746A61K36/752A61K36/888A61K36/9064A61P25/24A61K2300/00
Inventor 潘文亮王海涛王晶刘伟陈小敏鲍峰伟宁静邵璐莫志文赵辉马戎冯文宁牛丽娜阎瑾段海涛
Owner CHINA TOBACCO HEBEI INDUSTRIAL CO LTD
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