A method for estimating genomic breeding value integrating dominance effects

A genome and breeding value technology, which is applied in the field of livestock and poultry genetic selection, can solve the problems of not considering the dominant effect and the accuracy of the genome estimation breeding value, etc., and achieve the effects of easy convergence, fast calculation speed and improved accuracy
CN109101786AActive Publication Date: 2018-12-28ANIMAL SCI RES INST GUANGDONG ACADEMY OF AGRI SCI
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
ANIMAL SCI RES INST GUANGDONG ACADEMY OF AGRI SCI
Publication Date
2018-12-28

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Abstract

The invention discloses a genome breeding value estimation method for integrating dominant effect, which relates to the technical field of livestock and poultry genetic selection. The method comprisessteps identifying a reference group and a candidate group, the phenotype of the target traits of the reference population was determined, Genome-wide marker typing of reference population, quality control of gene marker of reference population, statistics of heterozygous marker deviation of reference population, formulation of genome marker re-coding rules, genome-wide marker typing of candidatepopulation, quality control of gene marker of candidate population, re-coding of genome marker and estimation of genome breeding value, etc. Based on the deviation degree between the phenotype of theheterozygous genotype and the phenotype of the homozygous genotype, the invention formulates coding rules, starts from the genomic marker end, re-codes the heterozygous genotype, causes the gene marker coding to include dominant effect, and then estimates the genomic breeding value. The invention is adapted to the needs of livestock and poultry genetic breeding, and can greatly improve the accuracy of genome estimation breeding value without increasing the complexity of the model.
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Description

technical field

[0001] The invention relates to the technical field of genetic selection and breeding of livestock and poultry, in particular to a genome breeding value estimation method integrating dominant effects. Background technique

[0002] Hybridization technology is widely used in the genetic selection and breeding of animals and plants such as pigs, chickens, cattle, rice and corn. Its application mainly has two aspects: on the one hand, it is used for the cultivation of new varieties, and the excellent characteristics of the parents are combined to form new varieties through hybridization technology. Another aspect is to use heterosis to improve production efficiency. Heterosis refers to the phenomenon that heterozygous offspring are better than the average value of their parents. Dominance effect is one of the most important causes of hybrid vigor, which refers to the effect of the interaction between alleles in the same gene locus. With the continuous developme...

Claims

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