Time optimization method for computer-aided layout design of digital microfluidic biochips

A computer-aided, biochip technology, applied in computing, electrical digital data processing, special data processing applications, etc., can solve problems such as not being well solved, and achieve high precision and efficiency, high efficiency, and low cost.

Active Publication Date: 2019-01-01
CHINA UNIV OF GEOSCIENCES (WUHAN)
View PDF2 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Microfluidic biochips perform biochemical reactions under certain experimental constraints. How to control microfluidic biochips to quickly complete al

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Time optimization method for computer-aided layout design of digital microfluidic biochips
  • Time optimization method for computer-aided layout design of digital microfluidic biochips
  • Time optimization method for computer-aided layout design of digital microfluidic biochips

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0044] In order to have a clearer understanding of the technical features, purposes and effects of the present invention, the specific implementation manners of the present invention will now be described in detail with reference to the accompanying drawings.

[0045] refer to image 3 , which is a flow chart of the time optimization method for computer-aided design of digital microfluidic biochip layout of the present invention, the method specifically includes:

[0046] S1. Establish a model of priority constraints, resource constraints, non-overlapping constraints, and fluid constraints:

[0047] Each standard simulation experiment of a microfluidic biochip has its own parameter settings. The upper limit of the size and time of the experiment is given in the input file. For example, the parameter setting Fixed: 10 10 360 indicates the size of the experiment The upper limit is 10*10, and the upper limit of time is 360. Each reagent or operation is also given a size occupied...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a time optimization method for computer-aided design layout of a digital microfluidic biochip, which comprises the following steps: establishing a model of four constraint conditions of priority constraint, resource constraint, overlap constraint and fluid constraint; establishing a target model of the total time of interlocking biochemical reactions on digital microfluidicbiochip; solving an optimal solution of the target model of the completion time according to the model of the four constraint conditions based on a Markov decision; according to the optimal solution,the realization process of the biochemical reaction on the digital microfluidic biochip being controlled. The invention can minimize the biochemical reaction time in the digital microfluidic biochip,and has the advantages of low cost, high precision and high efficiency.

Description

technical field [0001] The invention relates to the field of computer-aided design of digital microfluidic biochips, and more specifically relates to a time optimization method for computer-aided design layout of digital microfluidic biochips. Background technique [0002] First, the physical design of the microfluidic biochip is introduced. like figure 1 As shown, the microfluidic biochip is mainly composed of electrode plates, and the electrowetting electrodes are used to drive the droplets to move, mix, react, and store. The droplets store relevant reagent samples required for biochemical experiments. The droplets are sandwiched between two layers of indium tin oxide electrode plates. There are two non-reconfigurable resources here, optical detector and optical distribution port. The optical detector is used to detect whether each operation is running normally. As a special resource, its position is fixed during the manufacturing stage and in the There is no movement t...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): G06F17/50
CPCG06F30/392
Inventor 陈小岛刘东波王玥玮万超伟
Owner CHINA UNIV OF GEOSCIENCES (WUHAN)
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap