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Relapse-resistant medicine composition for treating condyloma acuminate and preparation method thereof

A kind of technology of condyloma acuminatum and composition, which is applied in the field of anti-relapse pharmaceutical composition for treating condyloma acuminatum, can solve the problems of high recurrence rate, inability to eradicate HPV infection, and inability to fundamentally eliminate condyloma acuminatum virus, etc., and achieve low recurrence rate and high efficacy The effect of high rate and high recovery rate

Inactive Publication Date: 2019-03-01
王玺
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Because CA is easy to relapse, the above treatment can only temporarily remove the wart body, but cannot eliminate the condyloma acuminatum virus at all, and cannot eradicate the infection of HPV. The effective rate is only about 30%, and the recurrence rate is extremely high, usually the lowest recurrence rate within 3 months. Up to 25% or more

Method used

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  • Relapse-resistant medicine composition for treating condyloma acuminate and preparation method thereof
  • Relapse-resistant medicine composition for treating condyloma acuminate and preparation method thereof
  • Relapse-resistant medicine composition for treating condyloma acuminate and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] A medicinal composition for treating condyloma acuminatum and preventing recurrence, comprising the following raw material components in parts by weight:

[0037] 10 parts of honeysuckle, 7 parts of dandelion, 9 parts of sophora flavescens, 9 parts of purslane, 7 parts of astragalus, 5 parts of Hedyotis diffusa, 8 parts of Cortex Phellodendri, 9 parts of Radix Isatidis, 3 parts of comfrey, 4 parts of coix seed, 7 parts of Atractylodes macrocephala share.

[0038] After weighing the above-mentioned raw materials, the preparation method steps are as follows:

[0039] (1) Honeysuckle pretreatment: Clean and sterilize the freshly picked honeysuckle, and then directly freeze at -10°C for 5 hours; put the frozen raw materials into a vacuum container with a vacuum pressure of 0.01MPa and a temperature of 50°C Perform dehydration and drying for 3 hours to obtain freeze-dried honeysuckle; place the freeze-dried honeysuckle in an environment with a temperature of 18° C. and a hu...

Embodiment 2

[0047] A medicinal composition for treating condyloma acuminatum and preventing recurrence, comprising the following raw material components in parts by weight:

[0048] 14 parts of honeysuckle, 5 parts of dandelion, 12 parts of flavescens, 8 parts of purslane, 9 parts of astragalus, 7 parts of Hedyotis diffusa, 5 parts of Cortex Phellodendri, 7 parts of Radix Isatidis, 5 parts of comfrey, 6 parts of coix seed, 5 parts of Atractylodes macrocephala share.

[0049] After weighing the above-mentioned raw materials, the preparation method of the pharmaceutical composition is the same as in Example 1, the difference is that:

[0050] Difference 1. In the purification process of purslane, triethylamine is used instead of N,N-dimethylcyclohexylamine.

[0051] Difference 2, the step d is operated as follows: first separate the upper layer solution obtained in step c, add water to it, and then feed CO 2 Gas, until the pH value of the solution is constant, stop the ventilation, let it...

Embodiment 3

[0053] A medicinal composition for treating condyloma acuminatum and preventing recurrence, comprising the following raw material components in parts by weight:

[0054] 12 parts of honeysuckle, 6 parts of dandelion, 10 parts of sophora flavescens, 9 parts of purslane, 8 parts of astragalus, 6 parts of Hedyotis diffusa, 6 parts of Cortex Phellodendri, 8 parts of Radix Isatidis, 4 parts of comfrey, 6 parts of coix seed, 6 parts of Atractylodes macrocephala 5 parts of licorice, 6 parts of white clove.

[0055] In the preparation method of the above-mentioned pharmaceutical composition, steps (1) and (2) are the same as in Example 1, and N,N-dimethylbutylamine is used in step (3) instead of N,N-dimethylcyclohexylamine, and the step ( 4) and (5) are the same as in Example 1, step (6) is as follows: put honeysuckle granules, Sophora flavescens, Astragalus root, Cortex Phellodendron, Radix Isatidis, Comfrey, Coix Seed and Atractylodes Rhizome together in a casserole, soak in water f...

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Abstract

The invention discloses a relapse-resistant medicine composition for treating condyloma acuminate and a preparation method thereof. The medicine composition comprises, by weight, 10-14 parts of flos lonicerae, 5-7 parts of herba taraxaci, 9-12 parts of radix sophorae flavescentis, 8-9 parts of herba portulacae, 7-9 parts of radix astragali, 5-7 parts of herba hedyotis diffusae, 5-8 parts of cortexphellodendri, 7-9 parts of radix isatidis, 3-5 parts of radix arnebiae seu lithospermi, 4-6 parts of semen coicis and 5-7 parts of rhizoma atractylodis macrocephalae. The preparation method includes:pretreating the flos lonicerae; pretreating the rhizoma atractylodis macrocephalae; purifying the herba portulacae; purifying the herba hedyotis diffusae and the herba taraxaci; putting all solid rawmaterial ingredients into a casserole, and soaking the ingredients with clear water; decocting for 15-20 minutes to obtain preferable 100ml of left medicine liquid, filtering with gauze for standby,and decocting again; adding concentrated liquids of the herba hedyotis diffusae and the herba taraxaci into a mixed medicine liquid, and finally adding a liposoluble ingredient to obtain the relapse-resistant medicine composition for treating the condyloma acuminate. The relapse-resistant medicine composition is a pure traditional Chinese medicine preparation, and is high in cure rate and capableof lowering recurrence rate.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, in particular to a recurrence-preventing pharmaceutical composition for treating condyloma acuminatum (CA). Background technique [0002] Condyloma acuminatum (CA), also known as condyloma acuminatum and genital warts, is epidermal tumor-like hyperplasia of genitals, perineum, and anus caused by human papillomavirus (HPV) infection. There are three types of infection: dominant infection, subclinical infection and recessive infection. It starts as light red papules, which gradually increase in size and merge into papillary, cauliflower-like or cockscomb growths. The roots may have peduncles. The surface appears white, stained or red due to the infiltration of secretions, with itching, burning pain and Stinky, proliferative and even huge genital warts. Sexual promiscuity is the reason for the transmission of this disease, which is popular all over the world. At present, STDS has reach...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8994A61P15/00A61P31/20A61K35/57
CPCA61K35/57A61K36/12A61K36/185A61K36/195A61K36/284A61K36/288A61K36/30A61K36/315A61K36/355A61K36/481A61K36/484A61K36/489A61K36/63A61K36/748A61K36/756A61K36/8994A61K2236/331A61K2236/333A61P15/00A61P31/20A61K2300/00
Inventor 王玺
Owner 王玺