Ointment containing heparinoid composition

A technology of composition and ointment, applied in the field of ointment containing heparin-like composition, can solve problems such as imperfect application of heparan-like composition, achieve the effects of inhibiting smooth muscle cell proliferation, improving blood circulation, and controlling inflammation

Inactive Publication Date: 2019-03-08
沈阳亿欣源生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, in the prior art, the application of the heparinoid composition on the skin, mucous membrane and other action sites is not perfect.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Example 1: An ointment containing a heparinoid composition, including 40 parts of heparin, 58.2 parts of matrix material, 0.1 part of dimethyl sulfoxide, 0.1 part of vitamin C, 0.1 part of potassium sorbate, and 0.5 part of collagen , 1 part of carboxymethyl cellulose, 3 parts of glycerin, 0.18 parts of preservatives.

Embodiment 2

[0028] Example 2: An ointment containing a heparinoid composition, including 20 parts of heparin, 67.5 parts of matrix material, 1 part of dimethyl sulfoxide, 0.125 parts of vitamin C, 0.125 parts of potassium sorbate, and 10 parts of collagen , 1.25 parts of carboxymethyl cellulose, 10 parts of glycerin, 2 parts of preservatives.

Embodiment 3

[0029] Example 3: An ointment containing a heparinoid composition, including 0.5 parts of heparin, 75.2 parts of matrix material, 2 parts of dimethyl sulfoxide, 0.2 parts of vitamin C, 0.2 parts of potassium sorbate, and 20 parts of collagen , 1.5 parts of carboxymethyl cellulose, 15 parts of glycerin, 5 parts of preservatives.

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PUM

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Abstract

The invention discloses ointment containing a heparinoid composition, and belongs to the field of biotechnology. The ointment containing the heparinoid composition is characterized by being prepared from the following components: 0.01-80 parts of mucopolysaccharide, 1-90 parts of a substrate material, 0.01-5 parts of a transdermal absorbent, 0.01-5 parts of an anti-oxidant, 0.01-5 parts of a bacteriostatic agent, 0.01-20 parts of a moisturizer, 0.1-20 parts of a thickener, 0.01-15 parts of a surfactant and 0.01-5 parts of a preservative. According to the invention, under cooperative action ofa cutin softener and a natural moisturizer, excessive increase of collagenous fibres can be inhibited, and formation of scars can be relieved; and moisture on the skin surface can be kept, so that thecollagenous fibres are softened; elasticity is strengthened; and softening effect on hypertrophic scars is achieved.

Description

technical field [0001] The invention belongs to the field of biotechnology, and in particular relates to an ointment containing a heparin-like composition used in medicines, medical equipment, cosmetics, disinfection products and the like. Background technique [0002] Heparinoid is a mucopolysaccharide. In 1948, when Jorpes and Gardell prepared heparin from liver and lung, they obtained a polysaccharide composed of D-glucuronic acid and D-glucosamine. These substances are similar in structure to heparin , but the degree of sulfation is low, and the anticoagulant activity is low, but after more sulfation, its properties change greatly. By combining with the surface of vascular endothelium, it promotes the release of endogenous amino polysaccharides with antithrombotic activity, which can improve local microcirculation, increase blood flow and blood flow velocity, thereby improving intermediate metabolism, promoting skin nutrition supply and waste excretion , play a role in ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/06A61K31/727A61K31/737A61P29/00A61P17/02A61P31/02A61P7/10
CPCA61K9/06A61K9/0014A61K31/727A61K31/737A61K47/22A61K47/38A61K47/42A61P7/10A61P17/02A61P29/00A61P31/02
Inventor 唐财坤关云成李丹钟鑫平王萌炜满国荣朱凯月肖秀梅马立强
Owner 沈阳亿欣源生物科技有限公司
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