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Aerosol containing heparin-like composition

A technology of composition and aerosol, applied in the field of aerosol containing heparan-like composition, can solve problems such as imperfect application of heparan-like composition, achieve inhibition of smooth muscle cell proliferation, promote supply and excretion of waste, inhibit The effect of overgrowth

Inactive Publication Date: 2019-03-22
沈阳亿欣源生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] However, in the prior art, the application of the heparinoid composition on the skin, mucous membrane and other action sites is not perfect.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Example 1: An aerosol containing a heparinoid composition, including 30 parts of heparin, 30 parts of Freon, 0.1 part of azone, 0.1 part of sodium sulfite, 0.1 part of sorbic acid, 3 parts of glycerin, 0.5 parts of collagen, preservative 0.18 parts of the agent.

Embodiment 2

[0026] Example 2: An aerosol containing a heparinoid composition, including 10 parts of heparin, 30 parts of freon, 1 part of azone, 0.125 parts of sodium sulfite, 0.125 parts of sorbic acid, 10 parts of glycerin, 10 parts of collagen, preservative 2 doses.

Embodiment 3

[0027] Example 3: An aerosol containing a heparinoid composition, including 0.5 parts of heparin, 30 parts of freon, 2 parts of azone, 0.2 parts of sodium sulfite, 0.2 parts of sorbic acid, 15 parts of glycerin, 20 parts of collagen, preservative 5 doses.

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PUM

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Abstract

The invention discloses an aerosol containing a heparin-like composition, and belongs to the field of biotechnology. The aerosol containing the heparin-like composition is characterized by comprising0.01-30 parts of mucopolysaccharide, 20-65 parts of a propellant, 0.01-5 parts of a transdermal absorbent, 0.01-5 parts of an antioxidant, 0.01-5 parts of a bacteriostatic agent, 0.01-15 parts of a surfactant, 0.01-20 parts of a moisturizing agent and 0.01-5 parts of a preservative. Under a synergistic action of a keratin softening agent and the natural moisturizing agent, the aerosol containing the heparin-like composition can inhibit the excessive growth of collagen fiber and reduce scar formation; the aerosol containing the heparin-like composition can retain moisture on the surface of skinto soften the collagen fiber and enhance the elasticity and has an effect of softening a hypertrophic scar.

Description

technical field [0001] The invention belongs to the field of biotechnology, and in particular relates to an aerosol containing a heparin-like composition used in medicines, medical equipment, cosmetics, disinfection products and the like. Background technique [0002] Heparinoid is a mucopolysaccharide. In 1948, when Jorpes and Gardell prepared heparin from liver and lung, they obtained a polysaccharide composed of D-glucuronic acid and D-glucosamine. These substances are similar in structure to heparin , but the degree of sulfation is low, and the anticoagulant activity is low, but after more sulfation, its properties change greatly. By combining with the surface of vascular endothelium, it promotes the release of endogenous amino polysaccharides with antithrombotic activity, which can improve local microcirculation, increase blood flow and blood flow velocity, thereby improving intermediate metabolism, promoting skin nutrition supply and waste excretion , play a role in r...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/12A61K47/42A61K47/10A61K31/726A61K31/727A61K31/737A61P29/00A61P31/04A61P31/10A61P31/12A61P7/10A61P17/02
CPCA61K9/0014A61K9/12A61K31/726A61K31/727A61K31/737A61K47/10A61K47/42A61P7/10A61P17/02A61P29/00A61P31/04A61P31/10A61P31/12
Inventor 唐财坤关云成李丹刘德华单颖满国荣朱凯月肖秀梅马立强
Owner 沈阳亿欣源生物科技有限公司
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