Cloud computing-based method for quality control and management of gene sequence data

A quality control management and gene sequencing technology, applied in the field of genetic engineering, can solve problems such as unfavorable subsequent analysis, search for sequencing data, and lack of understanding of data quality by experimenters, so as to improve experimental quality and accuracy.

Inactive Publication Date: 2019-04-05
江苏医联生物科技有限公司
View PDF3 Cites 6 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Separating the sample processing from the experiment link and the analysis link into two links, the experimenters do not understand the data quality, and cannot find deficiencies from the sequencing data. The analysts do not unde

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Cloud computing-based method for quality control and management of gene sequence data
  • Cloud computing-based method for quality control and management of gene sequence data
  • Cloud computing-based method for quality control and management of gene sequence data

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0024] In order to make the object, technical solution and advantages of the present invention clearer, the present invention will be further described below in conjunction with the accompanying drawings and specific embodiments. It should be understood that the specific embodiments described here are only used to explain the present invention, not to limit the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

[0025] A method for quality control management of gene sequence data based on cloud computing, including four links: sample clinical information management, experimental data management, data full-process quality control and analysis result management. The specific contents of each link are as follows:

[0026] (1) Sample clinical information management

[0027] In order to help experimenter...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention relates to a cloud computing-based method for quality control and management of gene sequence data. The method includes sample clinical information management, experimental data management, data whole process quality control and analysis result management. Testing items of the sample clinical information management includes genomic analysis and transcriptomics analysis, and the genomic analysis includes whole genome sequencing, whole exome sequencing and whole exome sequencing; the transcriptomic analysis includes gene fusion, variable splicing and differential expression analysis. Experimental links are closely connected with analytical links, an analyst can comprehensively understand clinical information, sample information and experimental results, subsequent analysis is facilitated, the accuracy of the analysis result is improved, and the method can help experimenters to understand the quality of sequencing data and thus reflect on shortcomings in the experimental process, the experimental quality is thus improved, and the need of practical use can be applied well.

Description

technical field [0001] The invention belongs to the technical field of genetic engineering, and in particular relates to a method for quality control and management of gene sequence data based on cloud computing. Background technique [0002] With the maturity and improvement of next-generation sequencing technology, genome sequencing has been widely used in the field of tumor research. Tumor samples can be divided into fresh frozen tissue, paraffin section tissue, blood and saliva according to the sampling source. Genome sequencing can be divided into whole genome sequencing, exome sequencing and target region capture sequencing according to the sequencing type. Whole Genome Sequencing (WGS) is the sequencing of the whole genome of different individuals or populations of humans. By comparing with the human reference genome, a wealth of genome-wide variation information is obtained, and biological information is carried out at the individual or population level. analyze. W...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): G16B20/30G16B25/00
Inventor 杨文婷陈亮
Owner 江苏医联生物科技有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap