SNP (Single Nucleotide Polymorphism) marker remarkably related to Australian white sheep hoof color grade, molecular marker and application

A technology of molecular markers and sheep, which is applied in the fields of genetic engineering and molecular biology, can solve the problems of undiscovered patent documents and achieve the effect of improving selection efficiency

Active Publication Date: 2019-04-26
天津奥群牧业有限公司
View PDF8 Cites 7 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Through the search of published patent documents, no published patent documents identical to this patent application have been found

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • SNP (Single Nucleotide Polymorphism) marker remarkably related to Australian white sheep hoof color grade, molecular marker and application
  • SNP (Single Nucleotide Polymorphism) marker remarkably related to Australian white sheep hoof color grade, molecular marker and application
  • SNP (Single Nucleotide Polymorphism) marker remarkably related to Australian white sheep hoof color grade, molecular marker and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0024] Embodiments of the present invention are described in further detail below in conjunction with the accompanying drawings:

[0025] A SNP marker that is significantly correlated with hoof color of Australian white sheep. The innovation is that the marker has two alleles, A and G, and is located in the ninth intron of the MITF gene.

[0026] The SNP marker is located at the 31603203 nucleotide site on chromosome 19 of the International Sheep Genome Version 4.0 Reference Sequence, and has an A / G polymorphism, and the SNP marker is located at the ninth inclusion of the melanin production-related transcription factor MITF gene Among them, the SNP markers were extremely significantly correlated with hoof color of Australian white sheep P<0.01.

[0027] The one with A / G polymorphism is g.31603203A / G.

[0028] The hoof color of Australian white sheep with GG genotype at the g.31603203A / G site is gray, the hoof color of Australian white sheep with AG genotype at g.31603203A / G s...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention belongs to the field of animal genetics and breeding, SNP (Single Nucleotide Polymorphism) markers and application and in particular relates to an SNP marker remarkably related to an Australian white sheep hoof color grade, a molecular marker and application. The marker is located on a 31603203rd nucleotide site (Chr19:31603203) on a No. 19 chromosome of an international sheep genome(Oar_v4.0) and the site has two alleles A and G and a 9th intron located on an MITF (Microphthalmia-Associated Transcription Factor) gene; a g.31603203A/G site has A/G polymorphism; an Australian white sheep hoof color of a GG gene type is black; the Australian white sheep hoof color of an AG gene type is grey; the Australian white sheep hoof color of an AA gene type is white. The SNP molecular marker provided by the invention can be used for assisting the breeding of an Australian white sheep new strain with uniform appearance and stable properties and cultivating a new variety by utilizingthe Australian white sheep.

Description

technical field [0001] The invention belongs to the fields of genetic engineering and molecular biology, and relates to animal genetic breeding, SNP markers and applications, in particular to a SNP marker, molecular markers and applications significantly related to hoof color of Australian white sheep. Background technique [0002] Australian White Sheep is a coarse-haired sheep bred by the Australian White Sheep Breeders Association of Australia, which integrates the excellent genes of White-headed Dorper sheep, Wanrui sheep, Hornless Dorset sheep and Texel sheep. A specialized mutton sheep breed. This breed was officially registered in Australia in October 2009 and launched in March 2011. In May 2011, the Australian White sheep was introduced from the Australian HVD Breeding Company by Tianjin Aoqun Animal Husbandry Co., Ltd. In view of the problems encountered in the introduction and local domestication, after the introduction adaptability test is completed, combined wi...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): C12Q1/6888C12N15/11
CPCC12Q1/6888C12Q2600/124C12Q2600/156
Inventor 张清峰林春建陈华卢小芳杨漫漫李斌王然王斌佐建明刘莹
Owner 天津奥群牧业有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap