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Traditional Chinese medicine composition assisting in treating constipation in children and preparation method thereof

A technology of adjuvant therapy and composition, applied in the field of medicine, can solve problems such as unsuitable for long-term application, poor taste, incarcerated stool, etc., and achieve the effect of improving bowel laxative, significant therapeutic effect, and alleviating drug properties

Inactive Publication Date: 2019-05-03
广西本草坊保健品有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, since it does not increase the tone of the colon, it should not be used in patients with slow bowel movements
Stimulant laxatives are mainly used for stool incarceration and those who need rapid defecation because they stimulate the intestinal mucosa and intestinal wall nerve plexus, and may cause large intestine muscle weakness and drug dependence, and are not suitable for long-term use
The main disadvantages of lubricating laxatives are poor taste and weak effect, and long-term use will cause malabsorption of fat-soluble vitamins
The main disadvantage of osmotic laxatives is that they ferment under the action of bacteria to produce gas, causing discomfort such as abdominal distension

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0054] Embodiment 1 Granules

[0055] Weigh hemp seed 40kg, mulberry leaves 25kg, radish seeds 30kg, cassia seeds 25kg, peach kernels 20kg; take all the medicinal materials, mix them and extract twice with 70% ethanol under reflux, each time the amount of ethanol is 6 times or 4 times the total weight of the medicinal materials , the extraction time is 2 hours and 1 hour respectively, the extracts are combined, filtered, and the filtrate is concentrated to a clear paste with a relative density of 1.20 when the filtrate is concentrated at 80 ° C. Add auxiliary materials fructooligosaccharide, dextrin, microcrystalline cellulose, carboxy Sodium methyl starch, magnesium stearate, polyethylene glycol, granulated, dried, granulated to obtain granules.

Embodiment 2

[0056] Embodiment 2 Granules

[0057] Weigh hemp seeds 45kg, mulberry leaves 28kg, radish seeds 34kg, cassia seeds 27kg, peach kernels 33kg; take all the medicinal materials, mix them and add water to extract 2 times, the amount of water added each time is equivalent to 12 times or 6 times the total weight of the medicinal materials. The extraction time is 3 hours, 2 hours, combined extracts, filtered, and the filtrate is concentrated to a clear paste with a relative density of 1.20 at 80°C, adding ethanol to make the alcohol content 70%, standing for 24 hours, filtered, and the filtrate is concentrated to The extract with a relative density of 1.20 at 80°C, add auxiliary materials microcrystalline cellulose, xylitol, inorganic salts, lactose, gelatin, talcum powder, crospovidone, ethanol, granulate, dry, granules to make granules.

Embodiment 3

[0058] Embodiment 3 capsules

[0059] Weigh hemp seeds 50kg, mulberry leaves 32kg, radish seeds 37kg, cassia seeds 30kg, peach kernels 36kg; take all the medicinal materials, mix them and add water to extract 2 times, the amount of water added each time is equivalent to 12 times or 8 times the total weight of the medicinal materials. The extraction time is 3 hours and 2 hours respectively. Combine the extracts, filter, and concentrate the filtrate to a clear paste with a relative density of 1.10 at 70°C. Add ethanol to make the alcohol content 40%, let it stand for 12 hours, filter, and concentrate the filtrate The extract with a relative density of 1.05 at 70°C was added to the capsule auxiliary materials lactose, starch, polyethylene glycol, cellulose derivatives, sodium carboxymethyl starch, and vegetable oil, and capsules were prepared according to a conventional scheme.

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Abstract

The invention discloses a traditional Chinese medicine composition assisting in treating constipation in children. The composition is prepared from hemp seeds, mulberry leaves, radish seeds, cassia seeds and peach kernels, is safe and mild, and has minimal side effects on the human body. The herbs are combined for use, perform excreting and dredging, perform excreting without damaging spleen and stomach, perform dredging without damaging healthy energy, and embody the characteristics of treating heat, treating accumulation, increasing liquid and moistening intestines. Therefore, the heat evilcan be cleared and excreted, the stagnation can be dredged, the large intestines can be moistened and smooth, the effects of clearing heat, dredging stagnation, eliminating accumulation, relaxing bowels, nourishing yin and benefiting qi can be achieved, and the composition is suitable for the treatment of functional constipation in children. In addition, the traditional Chinese medicine composition of the invention is scientific and reasonable in formula, small in side effects, simple in preparation method, low in preparation cost and capable of greatly reducing the physical and economic burden of the patient, and has great promotion value.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a traditional Chinese medicine composition for auxiliary treatment of children's constipation and a preparation method thereof. Background technique [0002] Functional constipation in children (Functional Constipation, FC) is one of the most common gastrointestinal disorders in children. FC is a common and frequently-occurring disease in childhood, with an incidence rate of 3-5%, accounting for 25% of children's digestive tract clinics. The harm of FC to the human body is not only manifested in affecting gastrointestinal function, but also affecting children's memory and intellectual development. In severe cases, it can also cause enuresis and fecal incontinence. Due to the low frequency of defecation, the feces stay in the intestine for a long time, and become dry and hard after the water is fully absorbed, making it difficult to pass. In severe cases, the intestinal wall may be oppre...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/736A61P1/10
Inventor 梁鹏曾梓强陆桂华曾梓宁黄琼连
Owner 广西本草坊保健品有限公司
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