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Making method of agkistrodon acutus freeze-dried powder for rheumatoid arthritis

A production method, the technology of five-step snake, applied in the direction of freeze-drying and transportation, medical preparations containing active ingredients, anti-inflammatory agents, etc., can solve the problem of loss of mobility, weakening of the curative effect of five-step snake rheumatoid arthritis, and untimely drying Putrefaction and other problems to achieve the effect of ensuring safety and high rheumatoid therapeutic effect

Active Publication Date: 2019-05-17
景德镇陈锋特种野生动物科技开发有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There is a huge population of patients with rheumatoid arthritis in my country. Patients often suffer from repeated torments of the disease, and some even lose their ability to move. However, the existing technologies often fail to achieve the expected therapeutic effect on rheumatoid arthritis, and cannot achieve a radical cure. Taking medicine for treatment can cause many adverse effects on the body
[0005] Five-step snake has a significant effect on rheumatoid arthritis, a worldwide problem. Research has found that the five-step snake has been dried before being powdered. The current drying method is drying and sun-drying, but the drying process must be strictly controlled. Only by controlling the temperature of the five-step snake during drying can the shelf-life activity be achieved. Even if the temperature of the five-step snake is controlled during drying, the active ingredients will lose a lot during the drying process, which will weaken the effect of the five-step snake on the treatment of rheumatoid arthritis. The curative effect; when the drying temperature exceeds 70 ℃, the active enzyme components contained in the five-step snake will be destroyed, and the efficacy will be greatly reduced; while the drying method is extremely easy to be polluted by flies and insects, and is also affected by the weather. Restrictions, if the drying is not timely, it will easily cause rancidity, and the quality of the medicinal materials cannot be guaranteed

Method used

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  • Making method of agkistrodon acutus freeze-dried powder for rheumatoid arthritis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] A preparation method for rheumatoid arthritis freeze-dried powder of five steps snake, comprising the following steps:

[0025] (1) freezing the fresh five-step snake to make it hibernate;

[0026] (2) Carry out pretreatment to the five-step snake in hibernation; cut off the head, remove internal organs and scales by laparotomy, clean up, and break the tissue in the five-step snake;

[0027] (3) Spray alcohol on the body of the five-step snake with broken tissue in the body;

[0028] (4) freeze-drying the five-step snake sprayed with alcohol;

[0029] (5) Pulverizing the freeze-dried five-step snake to obtain freeze-dried five-step snake powder for rheumatoid arthritis.

Embodiment 2

[0031] A preparation method for rheumatoid arthritis freeze-dried powder of five steps snake, comprising the following steps:

[0032] (1) Place the fresh five-step snake under the condition of minus 18°C ​​and freeze it for 2 hours to make it in a hibernation state, which is convenient for pretreatment of the five-step snake;

[0033] (2) Pre-treat the hibernating five-step snake; soak the hibernating five-step snake in water until slightly soft, cut off the head, remove the viscera and scales by laparotomy, clean it, and break it in five steps The tissues in the snake body; when broken, you can chop the five-step snake with a knife to destroy the tissues in the body. Because the skin of the five-step snake is relatively tough, the bones in the body are chopped, and the epidermis remains intact;

[0034] (3) Spraying concentration of 70% alcohol on the body of the broken five-step snake to remove the fishy smell on its body;

[0035] (4) The five-step snake sprayed with alco...

Embodiment 3

[0038] A preparation method for rheumatoid arthritis freeze-dried powder of five steps snake, comprising the following steps:

[0039] (1) Place the fresh five-step snake under the condition of minus 15°C and freeze it for 3 hours to make it in a hibernation state, which is convenient for pretreatment of the five-step snake;

[0040] (2) Pre-treat the hibernating five-step snake; soak the hibernating five-step snake in water until slightly soft, cut off the head, remove the viscera and scales by laparotomy, clean it, and break it in five steps The tissues in the snake body; when broken, you can chop the five-step snake with a knife to destroy the tissues in the body. Because the skin of the five-step snake is relatively tough, the bones in the body are chopped, and the epidermis remains intact;

[0041] (3) Spraying concentration of 70% alcohol on the body of the broken five-step snake to remove the fishy smell on its body;

[0042] (4) The five-step snake sprayed with alcoho...

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Abstract

The invention discloses a method for making agkistrodon acutus freeze-dried powder for rheumatoid arthritis. The making method of the agkistrodon acutus freeze-dried powder for the rheumatoid arthritis comprises the following steps that fresh agkistrodon acutus is frozen and kept in a hibernation state; the agkistrodon acutus in the hibernation state is pretreated; the head is cut off, paunching is conducted to remove the viscera and scales, cleaning is conducted thoroughly, and tissue in the body of the agkistrodon acutus is smashed; the body of the agkistrodon acutus with the tissue smashedin the body is sprayed with alcohol; the agkistrodon acutus sprayed with the alcohol is freeze-dried, and the agkistrodon acutus obtained after freeze-drying is smashed o obtain the agkistrodon acutusfreeze-dried powder for the rheumatoid arthritis. The method has the advantages that by adopting a freeze-drying technology, the agkistrodon acutus is dried completely, a smashing technology is adopted for processing, and the agkistrodon acutus freeze-dried powder is obtained; the active ingredients of the agkistrodon acutus freeze-dried powder are preserved to the maximum extent, and the high therapeutic effect on rheumatoid arthritis is achieved.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a method for preparing freeze-dried powder of five step snakes for rheumatoid arthritis. Background technique [0002] Five-legged viper, also known as "viper" and "agkistus acutus", belongs to the class Reptilia and Viperidae. It has a large triangular head, and the tip of its snout protrudes upward and forward. There are symmetrical large phosphorus on the top of the head. The head is dark brown and the body is The back is taupe, with a series of dark brown inverted "V"-shaped markings on both sides, and the abdomen is yellowish-white, with black round spots on both sides. Five-step snakes often live in mountain forests and feed on small mammals and birds. Legend has it that It is obviously absurd that a five-step snake can kill a person in five steps. Even the most poisonous snake in the world cannot poison people to death in such a short period of time, ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K35/583A61K9/19A61P29/00A61P19/02
Inventor 吴孟华黄子韩曹晖陈锋严胜军陈良启王智笑胡招龙
Owner 景德镇陈锋特种野生动物科技开发有限公司
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