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Traditional Chinese medicine suppository for treating acute cerebral infarct and preparation method of traditional Chinese medicine suppository

An acute stage, cerebral infarction technology, applied in the direction of suppository delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc., to achieve the effect of high safety factor

Active Publication Date: 2019-06-14
JIANGSU PROVINCE INST OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Honey Jiandao is the earliest traditional Chinese medicine suppository, derived from Zhang Zhongjing's "Treatise on Febrile and Miscellaneous Diseases". It is made of pure honey (pharmaceutical grade). It is safe, effective and has no side effects. It is still widely used in the treatment of chronic constipation. There are few research data on the application of infarction

Method used

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  • Traditional Chinese medicine suppository for treating acute cerebral infarct and preparation method of traditional Chinese medicine suppository

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Effect test

Embodiment 1

[0019] Take the crude drug of the present invention by the following parts by weight: honey (food grade), pig bile powder, mass ratio: 3:1.

[0020] Weigh honey and pig bile powder according to the above proportions, pure honey (pharmaceutical grade) is boiled and refined in a copper furnace, and after reaching a certain viscosity, blended with pig bile dry powder, blended evenly, continued to boil for 20 minutes, cooled to room temperature, Put it in a clean glass or ceramic container, seal it and store it at room temperature for later use.

[0021] Use the traditional Chinese medicine suppository of the present invention to treat the obstruction of internal energy or constipation in the acute stage of cerebral infarction, and adopt the method of administration through the anus, 1-2 times a day, 3-5ml each time.

Embodiment 2

[0023] Adopt the present invention to preliminarily carry out clinical authenticity research, clinical application more than 500 patients with acute cerebral infarction, the obtained clinical trial result situation is briefly summarized as follows:

[0024] 1. Case selection: 1,271 patients with acute cerebral infarction hospitalized in the Department of Neurology, Jiangsu Provincial Hospital of Integrated Traditional Chinese and Western Medicine, including 597 cases in the Chinese medicine suppository treatment group, 308 males and 289 females. The oldest was 92 years old and the youngest was 31 years old. , with an average age of 68.13±5.2 years; 674 cases in the blank control group, 348 males and 326 females, the oldest was 82 years old, the youngest was 29 years old, and the average age was 65.28±5.3 years old. There was no significant difference between the two groups in terms of age, sex, and illness (P>0.05), and they were comparable. The diagnostic criteria refer to th...

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Abstract

The invention discloses a traditional Chinese medicine suppository for treating acute cerebral infarct and a preparation method of the traditional Chinese medicine suppository. According to the traditional Chinese medicine suppository for treating the acute cerebral infarct and the preparation method of the traditional Chinese medicine suppository, the suppository is prepared for rectal administration and bowel relaxing by combining honey and pig's bile in a certain proportion, thereby being capable of more effectively purging the viscera to eliminate heat, descending the turbid, ascending thelucidity, removing pathogenic heat from the blood and toxic material from the body for resuscitation, and reducing the inflammatory reaction of the acute cerebral infarct to achieve the purpose of reducing cerebral edema, protecting the brain and improving long-term prognosis. The traditional Chinese medicine suppository has the advantages that the curative effect is definite, the suppository issimple, convenient and practicable, has no toxic and side effects, the effective rate reaches 86.55%, and the suppository has the good curative effect and potential clinical application value.

Description

technical field [0001] The invention relates to a traditional Chinese medicine external treatment suppository for treating acute cerebral infarction and improving prognosis, and belongs to the technical field of traditional Chinese medicine. Background technique [0002] Cerebral infarction is a common clinical disease with the characteristics of high morbidity, high mortality, high disability and high recurrence rate. Intracellular inflammatory response and brain tissue edema caused by cerebral ischemia and hypoxia are the main pathological manifestations in the acute stage of cerebral infarction. Reports at home and abroad believe that the dynamic changes of oxidative stress and immune inflammation mechanisms in serum and brain are closely related to the severity of stroke patients and the occurrence of disease terrorism. Commonly used clinical western medicines with anti-platelet aggregation and anti-arteriosclerosis, as well as Chinese patent medicines with the effects ...

Claims

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Application Information

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IPC IPC(8): A61K35/644A61K9/02A61P9/10A61P1/10A61K35/413
Inventor 刘红权王省成小兰李静波房铭铭高梅龚杰
Owner JIANGSU PROVINCE INST OF TRADITIONAL CHINESE MEDICINE
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