Device for stimulating cells with ultrasonic microbubbles and operating method thereof

Abstract

The invention is applicable to the field of medical equipment, and provides an ultrasonic microbubble stimulating cell device and an operation method thereof. The above-mentioned ultrasonic microbubble stimulation cell device includes a culture dish, a positioning frame and a base, a culture hole is arranged in the culture dish, a sealing film is arranged on the opening end, and a culture cover is arranged in the culture hole; A conduction component that stimulates cells and can adjust the distance from the culture dish; the base and the positioning frame are connected by an adjustment component. The above-mentioned operation method includes the steps of installing guide rods, connecting and assembling the conduction components, installing the positioning frame, installing the culture cover, injecting microbubbles, and installing the culture dish. An ultrasonic microbubble stimulating cell device and its operating method provided by the present invention can effectively prevent air bubbles from being mixed into the culture dish, ensure that the ultrasound can directly act on the microbubbles, and the area and intensity of the stimulating effect are controllable and easy to operate. The method is simple and convenient, has good versatility and wide application range.

Description

technical field [0001] The invention belongs to the field of medical devices, in particular to an ultrasonic microbubble stimulating cell device and an operation method thereof. Background technique [0002] With the development of science and technology, the cognition of ultrasound diagnosis and treatment is deepening, and the research of ultrasound stimulation has become a hot spot in medical treatment. Ultrasound stimulation has received more and more attention due to its safety, non-invasiveness, effectiveness and real-time performance. Nowadays, many laboratories in the world are conducting research on ultrasonic stimulation of cells, and ultrasonic stimulation microbubbles (or drug-loaded microbubbles) act on cells or lesions to achieve more ideal effects. However, since the microbubbles need to act on the cells at the bottom of the culture dish, the culture dish must be turned upside down to allow the microbubbles to float to the cells at the bottom of the culture di...

AI Technical Summary

Problems solved by technology

However, since the microbubbles need to act on the cells at the bottom of the culture dish, the culture dish must be turned upside down to allow the microbubbles to float to the cells at the bottom of the culture dish, and because air will enter the culture dish when the parafilm seals the culture dish and turns it upside down, it cannot be used. Ultrasound acts on microbubbles and stimulates cells

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