Evaluation method for allergy-relieving substance used for cosmetics

A cosmetic base and cosmetic technology, applied in the field of evaluation of sensitizing substances for cosmetics, can solve the problems of high cost, inability to truly reflect the anti-sensitivity effect of sensitizing substances on sensitive skin, and the duration of anti-allergic activity

Inactive Publication Date: 2019-07-02
SHANGHAI ZHONGYI DAILY CHEM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the current domestic research on sensitizing substances for cosmetics is still in its infancy, and the existing evaluation methods usually need to be completed in a specific environment, which has high requirements for operators, and there is often a gap between the experimental results and the results of human use. Differences, unable to truly reflect the anti-sensitivity effect of soothing substances on sensitive skin
Moreover, the use of in vivo models to measure the antiallergic activity of substances takes a long time and costs more

Method used

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  • Evaluation method for allergy-relieving substance used for cosmetics
  • Evaluation method for allergy-relieving substance used for cosmetics
  • Evaluation method for allergy-relieving substance used for cosmetics

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0108] Embodiment 1 A kind of facial mask for detecting sensitive skin

[0109] Preparation of facial mask liquid: The components of facial mask liquid are shown in the table below. Xanthan gum is first dispersed with 1,3-butanediol, then heated to 80-85°C with water, stirred and dissolved evenly, and kept warm for 15 minutes. After cooling down to 40-45°C, add phase B in turn, stir for 15-25 minutes, then turn to low speed stirring and cool to 30-35°C before discharging.

[0110] Preparation of facial mask: Fill the mask liquid into a mask bag containing a folded mask base material, wherein the mask base material used is a non-woven fabric, the area of ​​the mask base material is 350 square centimeters, and the pouring amount of the mask liquid is 17.5 g.

[0111] Table 1 uses phenoxyethanol as the composition of the facial mask liquid of sensitive detection agent

[0112]

Embodiment 2

[0113] Embodiment 2 A kind of facial mask for detecting sensitive skin

[0114] The components of the facial mask liquid are shown in the table below, and the preparation of the facial mask liquid and the facial mask is as described in Example 1. This mask is labeled Mask A.

[0115] Table 2 uses phenoxyethanol as the composition of the facial mask liquid of sensitive detection agent

[0116]

[0117]

Embodiment 3

[0118] Embodiment 3 A kind of facial mask for detecting sensitive skin

[0119] The components of the facial mask liquid are shown in the table below, wherein the facial mask substrate used is a non-woven fabric, and the area of ​​the facial mask substrate is 300 square centimeters, and the pouring amount of the facial mask liquid is 22.5g, and all the other are described in Example 1.

[0120] Table 3 uses phenoxyethanol as the composition of the facial mask liquid of sensitive detection agent

[0121]

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Abstract

The invention discloses a method for evaluating an allergy-relieving substance used for cosmetics by using a sensitive detection agent. The method includes the following steps: 1) a facial mask for detecting sensitive skin is prepared, the facial mask comprises a facial mask substrate and a facial mask liquid, and the facial mask liquid contains a cosmetic matrix and the sensitive detection agent;2) the allergy-relieving substance is added to the facial mask liquid of the step 1) to prepare the facial mask to which adding the allergy-relieving substance; and 3) the facial masks prepared by the steps 1) and 2) are separately applied to the face, a stimulus is perceived, and whether the allergy-relieving substance has allergy-relieving activity is evaluated according to a stimulus responsecondition of skin to the allergy-relieving substance. The evaluation method of the invention is simple in operation, is low in requirement for operation personnel, is more objective and truer in experimental result, and has the advantages of simple operation, objective and real experimental results, and high sensitivity.

Description

technical field [0001] The invention belongs to the technical field of cosmetics, and in particular relates to an evaluation method of a soothing substance for cosmetics. Background technique [0002] Sensitive skin specifically refers to a high-response state of the skin under physiological or pathological conditions, mainly on the face. The clinical manifestations are burning, tingling, itching and tightness when the skin is stimulated by physical, chemical and mental factors. Sensitivity and other subjective symptoms, with or without objective signs such as erythema, scales, and telangiectasia. The possible triggers of sensitive skin mainly include: (1) physical factors: such as season alternation, temperature change, sun exposure; (2) chemical factors: such as cosmetics, cleaning products, disinfection products, retinoic acid and other irritating external medicines, Environmental pollutants (such as smog, dust, exhaust), etc.; (3) Mental factors: such as anxiety, depres...

Claims

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Application Information

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IPC IPC(8): A61B5/00A61M35/00A61K8/34A61K8/365A61K8/37A61K8/42A61K8/46A61K8/9789A61Q19/00
CPCA61B5/441A61K8/34A61K8/365A61K8/37A61K8/42A61K8/466A61M35/00A61Q19/005A61K8/9789
Inventor 张芝华廖筝筝聂菁
Owner SHANGHAI ZHONGYI DAILY CHEM CO LTD
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