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Oral composition and method for inhibiting discoloration thereof

A composition and oral technology, applied in the directions of drug combination, oral care, cosmetic preparations, etc., can solve the problem of discoloration of preparations, and achieve the effects of inhibiting discoloration of preparations, good use feeling, and excellent appearance stability

Active Publication Date: 2019-07-02
LION CORP
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, tranexamic acid has a problem of discoloration of preparations over time due to mixing of ingredients

Method used

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  • Oral composition and method for inhibiting discoloration thereof
  • Oral composition and method for inhibiting discoloration thereof
  • Oral composition and method for inhibiting discoloration thereof

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Embodiment Construction

[0041] Hereinafter, the present invention will be described in further detail. The oral composition of the present invention contains (A) tranexamic acid, (B) cationized cellulose, and (C) tea leaf extract.

[0042] (A) Tranexamic acid is an active ingredient and has an anti-inflammatory effect.

[0043] (A) The blending amount of tranexamic acid is preferably 0.01 to 0.2% (mass%, hereinafter the same) of the entire composition, and more preferably 0.03 to 0.1% from the viewpoint of anti-inflammatory effect and discoloration suppression. Within this range, discoloration of the preparation can be sufficiently suppressed, and unpleasant taste can be sufficiently improved.

[0044] (B) The cationized cellulose has the effect of improving the oral cavity retention property of (A) component.

[0045] Examples of (B) cationized cellulose include fibers obtained by adding cationic groups such as dimethyl diallyl ammonium and 2-hydroxy-3(trimethylamino)propyl to cellulose derivative...

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Abstract

The present application provides an oral composition containing tranexamic acid which can suppress discoloration of a preparation after high-temperature storage and have excellent appearance stability, and a method for inhibiting discoloration thereof. The oral composition is characterized in comprising (A) tranexamic acid, (B) cationized cellulose, and (C) tea extract, by mass ratio, [(A)+(B)] / (C) is 0.5 to 200, and (B) / (C) is 0.2 to 100 by mass ratio; and the oral composition further contains One or more selected from (D) 3-octanol, 3-octyl acetate, and 3-octyl ketone and anthrone. The method for inhibiting discoloration is characterized in that in the oral composition containing the components (A) and (B), the component (C) is mixed so that The mass ratio of [(A)+(B)] / (C) and the massratio of (B) / (C) are within the above ranges respectively.

Description

Technical field [0001] The present invention relates to an oral composition containing tranexamic acid that can suppress discoloration of a preparation even after high-temperature storage and has excellent appearance stability, and a method for suppressing discoloration thereof. Background technique [0002] Tranexamic acid is a functional ingredient that has an anti-inflammatory effect on the gums. It is mixed into oral compositions as a periodontal disease preventive ingredient (Patent Document 1: Japanese Patent Laid-Open No. 2009-149565). In order to improve the cleaning effect, In order to improve the effect of tranexamic acid in the oral cavity of the dentifrice composition, patent document 2 (Japanese Patent Application Laid-Open No. 2001-226244) proposes the use of hydroxyethylcellulose-dimethyldiallylammonium. The effect of salt. [0003] In addition, Patent Documents 3 and 4 (Japanese Patent Laid-Open No. 2008-143870, Japanese Patent Laid-Open No. Sho 60-130509) s...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/44A61K8/73A61K8/9789A61Q11/00A61P1/02
CPCA61K8/44A61K8/731A61K8/9789A61Q11/00A61P1/02A61K8/411A61K31/195A61K47/46A61K2800/524
Inventor 石黑敬二饭泉刚太郎
Owner LION CORP
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