Coating composition for medical instruments

A technology of medical devices and compositions, applied in the direction of anti-corrosion coatings, anti-fouling/underwater coatings, coatings, etc., can solve the problems of inability to apply and promote, complex modification methods, high production costs, etc., and achieve excellent antibacterial properties and resistance Salt mist ability, excellent leveling effect, lubricity improvement effect

Inactive Publication Date: 2019-07-02
杨泰安
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In my country, restricted by medical coating materials, high-end interventional medical devices generally rely on imports, and the price is high
At the same time, the existing modification methods are relati

Method used

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  • Coating composition for medical instruments

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] A coating composition for medical devices, characterized in that it comprises the following components in parts by weight: the components in parts by weight: polyvinyl acetate 19, ethylene-vinyl acetate latex 8, polyhexaethylene gluconate Methylguanidine 7, azobisisobutyronitrile 5, polyvinyl alcohol 13, dispersant 7, thickener 5, Rana antibacterial peptide 31, defoamer 4, pH regulator 1, ferric oxide hollow magnetic nano Microsphere 42, titanium silicon carbide ceramic powder 31, distilled water 17.

[0015] The Rana antibacterial peptide of the present invention can achieve excellent antibacterial effect through the synergistic effect with polyhexamethylene guanidine gluconate. In particular, the Rana antibacterial peptide of the present invention is mixed into iron ferric oxide hollow magnetic nanospheres and titanium silicon carbide ceramic powder to form a long-term antibacterial layer on the surface of the paint.

[0016] Further, the dispersant is sodium lauryl ...

Embodiment 2

[0022] A coating composition for medical devices, characterized in that it includes the following components in parts by weight: the components in parts by weight: polyvinyl acetate 32, ethylene-vinyl acetate latex 17, polyhexaethylene gluconate Methylguanidine 18, azobisisobutyronitrile 11, polyvinyl alcohol 29, dispersant 12, thickener 9, Rana antibacterial peptide 38, defoamer 7, pH regulator 3, ferric oxide hollow magnetic nano Microsphere 59, titanium silicon carbide ceramic powder 47, distilled water 26.

[0023] Further, the dispersant is methyl pentanol.

[0024] Further, the thickener is zirconia oxide.

[0025] Further, the defoamer is tributyl phosphate.

[0026] Further, the pH regulator is diethanolamine.

Embodiment 3

[0028] A coating composition for medical devices, characterized in that it comprises the following components in parts by weight: components in parts by weight: polyvinyl acetate 23, ethylene-vinyl acetate latex 11, polyhexaethylene gluconate Methylguanidine 12, azobisisobutyronitrile 7, polyvinyl alcohol 16, dispersant 9, thickener 6, Rana antimicrobial peptide 33, defoamer 5, pH regulator 1.5, ferric oxide hollow magnetic nano Microsphere 45, titanium silicon carbide ceramic powder 34, distilled water 19.

[0029] Further, the dispersant is gull gum.

[0030] Further, the thickener is zirconia oxide.

[0031] Further, the defoamer is tributyl phosphate.

[0032] Further, the pH regulator is diethanolamine.

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PUM

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Abstract

The invention provides a coating composition for medical instruments. The coating composition is characterized by comprising the following components in parts by weight: 19-32 parts of polyvinyl acetate, 8-17 parts of ethylene-vinyl acetate latex, 7-18 parts of polyhexamethylene guanidine gluconate, 5-11 parts of azodiisobutyronitrile, 13-29 parts of polyvinyl alcohol, 7-12 parts of a dispersing agent, 5-9 parts of a thickening agent, 31-38 parts of a wood frog antibacterial peptide, 4-7 parts of a defoaming agent, 1-3 parts of a pH regulator, 42-59 parts of ferroferric oxide hollow magnetic nano microspheres, 31-47 parts of titanium silicon carbide ceramic powder and 17-26 parts of distilled water. The coating composition disclosed by the invention has excellent antibacterial capability and very good surface adhesion performance, and is suitable for being popularized and used in a large scale.

Description

technical field [0001] The invention belongs to the technical field of surface materials for medical devices, and in particular relates to a coating composition for medical devices. Background technique [0002] Minimally invasive interventional therapy is a new medical technology that uses specific puncture needles, guide wires or catheters under image guidance to accurately reach the lesion for diagnosis and treatment without opening human tissues. Medical polyurethane is a commonly used material for interventional catheters. When interventional devices enter or pull out of the human body and move in the human body, they need to have a lubricating surface to avoid damage to internal tissues. The medical polyurethane catheter itself is a hydrophobic material, and the surface does not have lubricity. Although lubricants or gel coatings can be used to obtain temporary lubricity, long-lasting lubricity can only be obtained by modifying the material itself or the surface of the...

Claims

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Application Information

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IPC IPC(8): C09D131/04C09D5/14C09D5/08A61L31/08A61L31/10A61L31/16A61L31/14A61L29/10A61L29/08A61L29/16A61L29/14
CPCA61L29/085A61L29/10A61L29/106A61L29/14A61L29/16A61L31/082A61L31/088A61L31/10A61L31/14A61L31/16A61L2300/206A61L2300/252A61L2300/404A61L2300/606A61L2420/06C08K2003/2244C08L2205/035C09D5/08C09D5/14C09D131/04C08L23/0853C08L79/00C08L29/04C08L89/00C08K13/04C08K3/34C08K7/24C08K3/22C08K5/521
Inventor 杨泰安
Owner 杨泰安
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