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A composition capable of anti-allergic, anti-itch and repairing

A technology of composition and extract, which is applied in the direction of drug combination, allergic diseases, skin care preparations, etc., and can solve the problems of irritation, pigmentation, poor effect and other problems of allergic skin

Active Publication Date: 2021-07-06
广州睿晞生化科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For the treatment of sensitive or allergic skin with multiple erythema, papules, desquamation, itching and other diseases, glucocorticoid hormones are needed, but if the hormones are used repeatedly for a long time, skin atrophy, telangiectasia, purpura, acne pigmentation abnormalities, photosensitivity will occur And other symptoms, bring endless troubles to modern women who love beauty, and hormone therapy is prone to dependence
[0004] At present, in the cosmetics market, major brands have launched products for people with sensitive skin, but there are few products that can effectively relieve allergic skin
Even anti-allergic cosmetics have defects such as poor effect, or even irritation to allergic skin, or even adding hormone drugs prohibited by the state to make them anti-allergic. Long-term use of this product will cause epidermal atrophy, pigmentation, etc., and cause irreversible damage to the skin

Method used

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  • A composition capable of anti-allergic, anti-itch and repairing

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1～5 and comparative example 1～3

[0021] See Table 1 for the formulations of the anti-allergic, anti-itch, and repairing compositions described in Examples 1-5 and Comparative Examples 1-3.

[0022] Table 1 The formula of the composition that can resist allergy, relieve itching and repair described in Examples 1 to 5 and Comparative Examples 1 to 3

[0023]

Embodiment 6

[0025] Composition Efficacy Determination of Anti-allergic Antipruritic Restoration described in Examples 1-5 and Comparative Examples 1-3

[0026] 1. Determination of the ability to inhibit hyaluronidase

[0027] The compositions described in Examples 1-5 and Comparative Examples 1-3 for anti-allergy, anti-pruritic repairing were respectively prepared into aqueous solutions with a concentration of 50 mg / mL as sample liquids. Take 0.1mL0.25mmol / LCaCl 2 solution and 0.5mL hyaluronidase solution and incubated at 37°C for 20min; add 0.5mL of sample solution, and continue to incubate at 37°C for 20min; add 0.5mL sodium hyaluronate solution and incubate at 37°C for 30min, and place it at room temperature for 5min; add 0.1mL of 0.4mol / LNaOH solution and 0.5mL acetylacetone solution, heated in a boiling water bath for 15min, and immediately cooled with ice water for 5min; added 1.0mL of Ehrlich reagent and diluted with 3.0mL absolute ethanol, left for 20min for color development, a...

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Abstract

The invention discloses a composition capable of resisting allergies, relieving itching, and repairing, which comprises the following components: oat β-glucan, root extract of Astragalus membranaceus, root extract of Radix Radix, Calendula flower extract, Albizia Julibrissin flower extract , Gastrodia elata root extract, Tetragalus alfalfa extract and Bacillus / soybean ferment extract. The composition combines oat β-glucan, Bacillus / soybean fermented product extract with plant antisensitizers (Scutellaria membranaceus root extract, Radix Radix Radix Radix Radix Radix Scutellariae membranaceus extract, Calendula flower extract, Albizia Julibrissin flower extract, Gastrodia elata Root extract and Fangji extract) compound, has a good anti-inflammatory effect, can effectively relieve skin sensitivity, reduce redness and swelling, and repair damaged skin. The invention also discloses a skin care product comprising the above-mentioned composition capable of anti-allergic, anti-itching and repairing.

Description

technical field [0001] The invention belongs to the technical field of cosmetics, and in particular relates to a composition capable of resisting allergies, relieving itching and repairing. Background technique [0002] With the continuous increase in the use of cosmetics and chemical agents in modern society, the increasing environmental pollution and the original allergens such as pollen and certain foods all increase the possibility of skin allergies. In addition, various other reasons also make the population of sensitive skin continue to increase. [0003] At present, contact dermatitis is the most common among the six major cosmetic dermatological diseases, and its incidence rate accounts for 82.6% of the total incidence of cosmetic dermatological diseases. Allergies seem to be a nightmare that people follow on the road of pursuing health and beauty. For the treatment of sensitive or allergic skin with multiple erythema, papules, desquamation, itching and other disea...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/99A61K8/9794A61K8/9789A61K8/73A61Q19/00A61P17/04A61P37/08
CPCA61K8/73A61K8/99A61K2800/85A61Q19/00A61Q19/005A61K8/9789A61K8/9794A61P17/04A61P37/08
Inventor 吴文基
Owner 广州睿晞生化科技有限公司
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