Production system for polypeptide drugs

A production system and drug technology, applied in the field of polypeptide drug preparation, can solve the problems of no safety, environmental protection, inability to industrialize, and unguaranteed reaction conditions, etc., to achieve product quality assurance, prevent excessive pressure, and high degree of automation Effect

Inactive Publication Date: 2019-09-27
上海友尹化工科技有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] 1. Staying in the laboratory stage, the main reaction equipment (vessel) is not highly automated, and the single-batch production capacity is low, so it cannot be industrialized;
[0006] 2. There are no corresponding measures in terms of safety, environmental protection, and occupational health, and the risks in terms of safet

Method used

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  • Production system for polypeptide drugs
  • Production system for polypeptide drugs

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Embodiment Construction

[0029] The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments.

[0030] In the description of the present invention, it should be understood that the terms "upper", "lower", "front", "rear", "left", "right", "top", "bottom", "inner", " The orientation or positional relationship indicated by “outside” is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present invention and simplifying the description, and does not indicate or imply that the device or element referred to must have a specific orientation to The specific orientation structure and operation cannot be understood as a limitation of the present invention.

[0031] Referen...

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Abstract

The invention discloses a production system for polypeptide drugs. The production system comprises a polypeptide synthesis production system and a polypeptide cracking production system, wherein the polypeptide synthesis production system comprises an activation tank, a first buffer tank, a second buffer tank, a synthesis reactor, a first material storage tank, a second material storage tank, a third material storage tank, a fourth material storage vat, a first centrifugal pump, a second centrifugal pump and a waste liquid treating system; discharging openings of the activating tank, the first buffer tank and the second buffer tank are all simultaneously connected with the synthesis reactor and the waste liquid treating system; a discharging opening of the synthesis reactor is divided into two paths; one path of the discharging opening discharges resin, and the other path of the discharging opening is connected with the waste liquid treating system. The production system for the polypeptide drugs, provided by the scheme, can realize automatic preparation of the polypeptide drugs, and is high in automatic degree as well as safe and reliable in preparation process; meanwhile, the pollution to environment can be effectively avoided and thereby better environment friendliness is realized.

Description

Technical field [0001] The present invention relates to the technical field of polypeptide medicine preparation, in particular to a production system for polypeptide medicine. Background technique [0002] Many active substances in the human body are in the form of peptides, involving hormones, nerves, cell growth and reproduction in the human body. They are important physiological regulators of the human body. They can comprehensively regulate the physiological functions of the human body, enhance and exert the physiological activities of the human body. Important biological function. [0003] Modern people cause the loss and loss of peptides in the human body due to various factors, and the ability to synthesize peptides is greatly weakened. If the human body lacks peptides, it is necessary to supplement synthetic peptides. The market demand for peptides is very large. [0004] However, the existing preparation technology of peptide drugs generally has the following disadvantages:...

Claims

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Application Information

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IPC IPC(8): C07K1/36C07K1/34C07K1/30
CPCC07K1/303C07K1/34C07K1/36
Inventor 向兵张燕霞王波陈志华
Owner 上海友尹化工科技有限公司
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