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System and method for producing morin through phellinus igniarius fermentation and resin separation and coupling

A technology of resin separation and Morin, applied in the direction of microorganism-based methods, biochemical equipment and methods, methods of supporting/immobilizing microorganisms, etc., can solve problems such as premature aging of the body that cannot be ruled out, and achieve increased production and simplified separation Process, cost reduction effect

Pending Publication Date: 2019-10-15
FUJIAN NORMAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

This substance exists in plants or microorganisms, but when it is extracted from these materials, the produced Morphein also has a feedback inhibitory effect on the body itself, and when the concentration of Morphein is too large, it cannot be ruled out that it may lead to premature detoxification of the body. Situation of decline
At present, the metabolic pathway for the synthesis of Morin in the body has not been clarified, and molecular biology methods cannot solve this problem

Method used

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  • System and method for producing morin through phellinus igniarius fermentation and resin separation and coupling
  • System and method for producing morin through phellinus igniarius fermentation and resin separation and coupling
  • System and method for producing morin through phellinus igniarius fermentation and resin separation and coupling

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Embodiment 1

[0031] A system for producing Phellinus using Phellinus Fermentation and resin separation coupling, such as figure 1 As shown, it includes: an air compressor 1, a reactor, a chromatographic column 2 and an eluting device connected in sequence through pipelines.

[0032] In order to measure the content of air entering the reactor, an air flowmeter 21 is set on the pipeline that the air compressor 1 communicates with the reactor; A 0.2 μm air filter is also installed on the connected pipeline.

[0033] The reactor includes a fermentation bottle 3, a heating device for heating the material in the fermentation bottle 3, and a stirring device for stirring the material in the fermentation bottle 3; 3 the heating jacket 5 on the outer wall and the heating controller 6 connected with the thermocouple 4; the stirring device is a magnetic stirrer 7, and the fermentation bottle 3 is placed on the magnetic stirrer 7.

[0034] In order to transport the material in the reactor to the chro...

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Abstract

The invention provides a system and method for producing morin through phellinus igniarius fermentation and resin separation and coupling. The system comprises an air compressor, a reactor, a chromatography column and an eluting device which are sequentially connected through a pipeline, wherein the reactor comprises fermentation bottles, a heating device for heating substances in the fermentationbottles, and a stirring device for stirring substances in the fermentation bottles; a first peristaltic pump and a first pipeline switch are arranged on a pipeline which communicates with the chromatography column, in the reactor; filtering gauze is also arranged at the bottom of the pipeline; a fifth pipeline switch and a sixth pipeline switch are arranged at the lower end of the chromatographycolumn; and the eluting device comprises an eluting bottle I, an eluting bottle II and the like. The heterotopic separation technique of resin adsorption is used for the process of producing the morinthrough phellinus igniarius fermentation, and a new thinking is provided for production of the morin through phellinus igniarius fermentation and separation of the morin; and through the operation, the yield of the morin can be increased, the subsequent separation technology can also be simplified, the cost can be reduced, and the operation has high practicality.

Description

technical field [0001] The invention belongs to the technical field of extracting active components of edible and medicinal fungi, and in particular relates to a system and method for producing Phellinus by coupling Phellinus fermentation and resin separation. Background technique [0002] Phellinus japonica, also known as mulberry ear, Husun ​​eye, plum tree fungus, is a rare and precious perennial large-scale edible and medicinal fungus, belonging to Basidiomycota, Hymenomycetes, Polyporales, Polyporaceae and Phelliunus mainly parasitize on the trunks of broad-leaved trees such as mulberry, birch and poplar, and have the reputation of "forest gold". According to current research, Phellinus contains no less than a hundred kinds of chemical substances, and most of these chemical substances have pharmacological activity, can treat various diseases, and have good application and development prospects. [0003] Pherin belongs to polyphenolic compounds, which can be used as nat...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12M1/38C12M1/34C12M1/24C12M1/12C12M1/04C12M1/02C12M1/00C12P17/06C07D311/30C12R1/645
CPCC12M23/08C12M27/02C12M29/04C12M41/00C12M41/22C12M47/10C12P17/06C07D311/30
Inventor 朱虎王颖璐常爱平李丽鱼晓丹何侨妹刘奥
Owner FUJIAN NORMAL UNIV
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