Antibacterial composition and preparation method and application thereof
A technology of composition and extract, which is applied in the field of daily chemicals, can solve problems such as colony disorder, large skin irritation, and lesions, and achieve the effect of restoring the balance of flora and maintaining a healthy bacterial environment in the vagina
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Embodiment 1
[0034] Each group of antibacterial composition formula of table 1
[0035] group 1 group 2 group 3 group 4 Group 5 Group 6 pituitary bark 6 servings 8 servings 10 copies 8 servings 8 servings -- dandelion 8 servings 10 copies 13 copies -- 10 copies -- coptis 9 servings 12 copies 15 copies 12 copies -- 12 copies wintergreen 5 copies 10 copies 12 copies -- -- 9 servings
[0036] Grind Pittogonia bark, dandelion, coptis, and wintergreen, extract with water at 120°C for 90 minutes, collect the filtrate by filtration, concentrate to 1g (crude drug) / ml, and obtain extract, refrigerate at 4°C for later use;
[0037] The extract was extracted with ethanol at 25° C. for 30 minutes, the supernatant was collected by centrifugation, and the extract was obtained by drying.
[0038] 1. In vitro antibacterial experiment
[0039] The different compositions act on Escherichia coli, Staphylococcus aureus and...
Embodiment 2
[0045] Adopt the antibacterial composition in the group 3 in the embodiment 1 and the group 4 in the comparative example to prepare the antibacterial gel, formula such as table 2:
[0046] Table 3 antibacterial gel formula
[0047]
[0048] The preparation method of gel is:
[0049] Boil the water and cool it down to 70-75°C, add hydrolyzed collagen, paraphyllan, and cellulose, stir to dissolve completely, homogenize at a speed of 8000r / min for 3 minutes, lower the temperature to 45°C, and then add plant extracts and the antibacterial composition, and then under the condition that the rotation speed is 450r / min, stir evenly for 25min, add lactic acid and stir evenly, adjust the pH, and discharge to prepare the feminine care gel.
[0050] product evaluation
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