1 results about "Leonurus cardiaca extract" patented technology

This invention belongs to the field of traditional Chinese medicine and natural product technology, specifically relating to the use of Leonurus japonicus extract in the preparation of antidepressant drugs. This invention uses 70% ethanol extraction to prepare Leonurus japonicus extract. This extraction method reduces extraction costs, shortens production time, increases extract yield, increases the extraction rate of effective components, and increases enterprise production efficiency. This invention also uses multiple depression models to verify the antidepressant activity of Leonurus japonicus extract, including a chronic unpredictable mild stress-induced depression model, a chronic corticosterone injection-induced depression model, and an ovariectomy combined with hormone withdrawal-induced depression model. The results show that Leonurus japonicus extract has a significant antidepressant effect in experimental animals. The antidepressant effect of the Leonurus japonicus extract of this invention is not obvious compared to the characteristics of traditional gynecological drugs, and it focuses on hormone-related depression, demonstrating the therapeutic value of Leonurus japonicus extract in the clinical classification of depression.